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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM14E All Species: 1.82
Human Site: S65 Identified Species: 3.64
UniProt: Q6UXP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UXP3 NP_001116700.1 125 13608 S65 R N P K E H L S S P V Y I W D
Chimpanzee Pan troglodytes XP_001167565 114 12030 Q55 L A G L G A Y Q L Y Q D P R N
Rhesus Macaque Macaca mulatta XP_001094148 114 12006 Q55 L A G L G S Y Q M S Q D P R N
Dog Lupus familis XP_535885 114 11732 Q55 L A G L G A Y Q L S Q D P R N
Cat Felis silvestris
Mouse Mus musculus Q9CQN6 114 11623 Q55 L A G L G A Y Q L S Q D P R N
Rat Rattus norvegicus Q924P2 115 11757 L56 A G L G A Y Q L S Q D P R N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514626 142 14235 S62 I G Y A K A G S V P S L A A G
Chicken Gallus gallus XP_418940 107 11066 L48 A G L G A Y Q L S Q N P S N V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q0P436 107 10663 T48 A G F G A Y Q T S Q D P G N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1K0 112 11563 P53 H L N S Q D T P R P L L Q L G
Honey Bee Apis mellifera XP_001120404 113 11638 N54 Q T S Q D P T N I G L S I A A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795741 101 10475 Y42 L F G A M A G Y G A S L T S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28 28.7 39.2 N.A. 36 39.2 N.A. 33 32.7 N.A. 32 N.A. 30.3 32.7 N.A. 29.6
Protein Similarity: 100 48 50.4 55.2 N.A. 52.7 53.5 N.A. 47.1 41.5 N.A. 46.4 N.A. 40 48.7 N.A. 44.8
P-Site Identity: 100 0 0 0 N.A. 0 6.6 N.A. 13.3 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 6.6 6.6 6.6 N.A. 6.6 13.3 N.A. 20 13.3 N.A. 20 N.A. 20 40 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 34 0 17 25 42 0 0 0 9 0 0 9 17 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 9 0 0 0 0 17 34 0 0 9 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 34 42 25 34 0 17 0 9 9 0 0 9 0 17 % G
% His: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 9 0 0 0 17 0 9 % I
% Lys: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 42 9 17 34 0 0 9 17 25 0 17 25 0 9 0 % L
% Met: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 0 0 0 9 0 0 9 0 0 25 34 % N
% Pro: 0 0 9 0 0 9 0 9 0 25 0 25 34 0 0 % P
% Gln: 9 0 0 9 9 0 25 34 0 25 34 0 9 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 9 0 0 0 9 34 0 % R
% Ser: 0 0 9 9 0 9 0 17 34 25 17 9 9 9 0 % S
% Thr: 0 9 0 0 0 0 17 9 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 9 0 0 25 34 9 0 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _