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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM14E
All Species:
1.52
Human Site:
Y69
Identified Species:
3.03
UniProt:
Q6UXP3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXP3
NP_001116700.1
125
13608
Y69
E
H
L
S
S
P
V
Y
I
W
D
L
A
R
Y
Chimpanzee
Pan troglodytes
XP_001167565
114
12030
D59
G
A
Y
Q
L
Y
Q
D
P
R
N
V
W
G
F
Rhesus Macaque
Macaca mulatta
XP_001094148
114
12006
D59
G
S
Y
Q
M
S
Q
D
P
R
N
V
W
V
F
Dog
Lupus familis
XP_535885
114
11732
D59
G
A
Y
Q
L
S
Q
D
P
R
N
I
W
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQN6
114
11623
D59
G
A
Y
Q
L
S
Q
D
P
R
N
V
W
V
F
Rat
Rattus norvegicus
Q924P2
115
11757
P60
A
Y
Q
L
S
Q
D
P
R
N
V
W
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514626
142
14235
L66
K
A
G
S
V
P
S
L
A
A
G
L
F
F
G
Chicken
Gallus gallus
XP_418940
107
11066
P52
A
Y
Q
L
S
Q
N
P
S
N
V
W
I
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q0P436
107
10663
P52
A
Y
Q
T
S
Q
D
P
G
N
I
W
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K0
112
11563
L57
Q
D
T
P
R
P
L
L
Q
L
G
T
S
L
F
Honey Bee
Apis mellifera
XP_001120404
113
11638
S58
D
P
T
N
I
G
L
S
I
A
A
T
S
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795741
101
10475
L46
M
A
G
Y
G
A
S
L
T
S
K
N
P
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
28.7
39.2
N.A.
36
39.2
N.A.
33
32.7
N.A.
32
N.A.
30.3
32.7
N.A.
29.6
Protein Similarity:
100
48
50.4
55.2
N.A.
52.7
53.5
N.A.
47.1
41.5
N.A.
46.4
N.A.
40
48.7
N.A.
44.8
P-Site Identity:
100
0
0
0
N.A.
0
6.6
N.A.
20
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
20
20
20
N.A.
20
13.3
N.A.
26.6
13.3
N.A.
20
N.A.
33.3
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
42
0
0
0
9
0
0
9
17
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
17
34
0
0
9
0
0
0
9
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
42
% F
% Gly:
34
0
17
0
9
9
0
0
9
0
17
0
0
9
9
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
17
0
9
9
9
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
9
17
25
0
17
25
0
9
0
17
0
9
34
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
25
34
9
0
9
0
% N
% Pro:
0
9
0
9
0
25
0
25
34
0
0
0
9
0
0
% P
% Gln:
9
0
25
34
0
25
34
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
9
34
0
0
0
9
0
% R
% Ser:
0
9
0
17
34
25
17
9
9
9
0
0
17
17
0
% S
% Thr:
0
0
17
9
0
0
0
0
9
0
0
17
0
0
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
17
25
17
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
25
34
0
0
% W
% Tyr:
0
25
34
9
0
9
0
9
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _