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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP12
All Species:
8.18
Human Site:
S85
Identified Species:
22.5
UniProt:
Q6UXS9
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXS9
NP_001216
341
38907
S85
W
N
S
K
K
Q
L
S
S
D
I
S
S
D
G
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Y37
G
I
S
L
D
N
S
Y
K
M
D
Y
P
E
M
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
S85
L
S
H
P
K
Q
L
S
L
E
Y
Q
H
E
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08736
419
47835
S85
A
N
S
Q
E
Q
L
S
L
Q
F
S
N
D
E
Rat
Rattus norvegicus
Q920D5
420
47818
S85
A
N
S
D
K
Q
L
S
L
Q
F
P
S
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509500
456
52101
A156
C
K
K
N
P
F
V
A
A
K
L
G
L
S
A
Chicken
Gallus gallus
Q98943
424
47941
E97
A
E
M
I
L
K
T
E
S
S
L
R
H
G
I
Frog
Xenopus laevis
P55867
382
43370
E98
H
A
P
S
P
I
Q
E
H
N
E
D
T
I
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
R154
S
R
A
R
S
R
S
R
S
R
A
L
H
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.2
66.5
N.A.
N.A.
49.1
48.3
N.A.
35.9
23.8
35.5
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
100
36.6
74.1
N.A.
N.A.
63.4
61.6
N.A.
51.7
41.2
50
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
100
6.6
26.6
N.A.
N.A.
46.6
53.3
N.A.
0
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
46.6
N.A.
N.A.
66.6
53.3
N.A.
26.6
20
13.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
12
12
0
0
0
0
12
12
0
12
0
0
0
12
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
0
0
0
0
12
12
12
0
34
12
% D
% Glu:
0
12
0
0
12
0
0
23
0
12
12
0
0
23
12
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
23
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
12
0
12
12
% G
% His:
12
0
12
0
0
0
0
0
12
0
0
0
34
0
0
% H
% Ile:
0
12
0
12
0
12
0
0
0
0
12
0
0
12
12
% I
% Lys:
0
12
12
12
34
12
0
0
12
12
0
0
0
0
12
% K
% Leu:
12
0
0
12
12
0
45
0
34
0
23
12
12
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
12
% M
% Asn:
0
34
0
12
0
12
0
0
0
12
0
0
12
0
0
% N
% Pro:
0
0
12
12
23
0
0
0
0
0
0
12
12
0
0
% P
% Gln:
0
0
0
12
0
45
12
0
0
23
0
12
0
0
0
% Q
% Arg:
0
12
0
12
0
12
0
12
0
12
0
12
0
0
0
% R
% Ser:
12
12
45
12
12
0
23
45
34
12
0
23
23
23
23
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
12
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _