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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GFRAL
All Species:
9.7
Human Site:
S379
Identified Species:
35.56
UniProt:
Q6UXV0
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXV0
NP_997293.2
394
44518
S379
K
L
R
T
S
R
I
S
S
K
A
R
D
P
S
Chimpanzee
Pan troglodytes
XP_001157000
394
44448
S379
K
L
R
T
S
R
I
S
S
K
A
R
D
P
S
Rhesus Macaque
Macaca mulatta
XP_001104929
394
44593
S379
K
L
R
T
S
R
I
S
S
K
A
R
D
P
S
Dog
Lupus familis
XP_538972
430
48516
Y410
P
F
N
G
E
V
I
Y
A
V
M
C
M
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6SJE0
393
43945
R379
L
R
I
Q
S
E
K
R
D
P
S
S
I
E
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505459
394
44193
F379
E
E
Y
L
C
K
I
F
H
H
I
L
H
S
R
Chicken
Gallus gallus
XP_419904
463
52410
C416
P
C
S
A
N
A
D
C
K
A
A
Y
I
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
93.1
69
N.A.
70.3
N.A.
N.A.
49.2
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.6
78.5
N.A.
82.4
N.A.
N.A.
62.1
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
6.6
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
15
0
0
15
15
58
0
0
0
0
% A
% Cys:
0
15
0
0
15
0
0
15
0
0
0
15
0
0
0
% C
% Asp:
0
0
0
0
0
0
15
0
15
0
0
0
43
0
0
% D
% Glu:
15
15
0
0
15
15
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
15
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
15
15
0
0
15
0
0
% H
% Ile:
0
0
15
0
0
0
72
0
0
0
15
0
29
0
15
% I
% Lys:
43
0
0
0
0
15
15
0
15
43
0
0
0
0
0
% K
% Leu:
15
43
0
15
0
0
0
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% M
% Asn:
0
0
15
0
15
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
29
0
0
0
0
0
0
0
0
15
0
0
0
43
0
% P
% Gln:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
43
0
0
43
0
15
0
0
0
43
0
0
15
% R
% Ser:
0
0
15
0
58
0
0
43
43
0
15
15
0
29
43
% S
% Thr:
0
0
0
43
0
0
0
0
0
0
0
0
0
15
0
% T
% Val:
0
0
0
0
0
15
0
0
0
15
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
0
15
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _