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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFRAL All Species: 1.52
Human Site: S387 Identified Species: 5.56
UniProt: Q6UXV0 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UXV0 NP_997293.2 394 44518 S387 S K A R D P S S I Q I P G E L
Chimpanzee Pan troglodytes XP_001157000 394 44448 P387 S K A R D P S P I Q I P G E L
Rhesus Macaque Macaca mulatta XP_001104929 394 44593 L387 S K A R D P S L S Q V P G E L
Dog Lupus familis XP_538972 430 48516 T418 A V M C M T V T C G I L L L V
Cat Felis silvestris
Mouse Mus musculus Q6SJE0 393 43945
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505459 394 44193 S387 H H I L H S R S C F S K L H D
Chicken Gallus gallus XP_419904 463 52410 W424 K A A Y I S N W G T M L H V E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 93.1 69 N.A. 70.3 N.A. N.A. 49.2 22.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 96.6 78.5 N.A. 82.4 N.A. N.A. 62.1 38.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 80 6.6 N.A. 0 N.A. N.A. 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 26.6 N.A. 0 N.A. N.A. 6.6 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 58 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 15 0 0 0 0 29 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 43 0 0 0 0 0 0 0 0 0 15 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 43 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 15 15 0 0 43 0 0 % G
% His: 15 15 0 0 15 0 0 0 0 0 0 0 15 15 0 % H
% Ile: 0 0 15 0 15 0 0 0 29 0 43 0 0 0 0 % I
% Lys: 15 43 0 0 0 0 0 0 0 0 0 15 0 0 0 % K
% Leu: 0 0 0 15 0 0 0 15 0 0 0 29 29 15 43 % L
% Met: 0 0 15 0 15 0 0 0 0 0 15 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 43 0 15 0 0 0 43 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % Q
% Arg: 0 0 0 43 0 0 15 0 0 0 0 0 0 0 0 % R
% Ser: 43 0 0 0 0 29 43 29 15 0 15 0 0 0 0 % S
% Thr: 0 0 0 0 0 15 0 15 0 15 0 0 0 0 0 % T
% Val: 0 15 0 0 0 0 15 0 0 0 15 0 0 15 15 % V
% Trp: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _