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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOOL
All Species:
9.39
Human Site:
S186
Identified Species:
20.67
UniProt:
Q6UXV4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXV4
NP_940852.3
268
29159
S186
V
K
S
L
W
T
K
S
S
K
E
E
S
L
P
Chimpanzee
Pan troglodytes
XP_521156
268
29148
S186
V
K
S
L
W
T
K
S
S
K
E
E
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001082461
279
30617
S197
V
K
S
L
W
K
K
S
S
K
E
E
S
L
P
Dog
Lupus familis
XP_850962
306
33240
I224
V
K
S
L
W
T
K
I
N
K
K
E
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q78IK4
265
29242
W183
F
Q
A
I
K
S
L
W
T
Q
K
S
E
N
E
Rat
Rattus norvegicus
NP_001014127
254
28219
T173
Q
A
I
K
S
M
W
T
Q
S
S
E
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517543
213
21966
D132
W
A
G
S
G
A
R
D
S
T
Q
V
A
A
H
Chicken
Gallus gallus
Q5ZK55
272
30116
K183
V
R
S
L
W
T
K
K
E
D
A
S
K
L
Q
Frog
Xenopus laevis
NP_001088003
301
33340
N185
L
S
S
F
W
K
A
N
I
N
K
A
Q
T
Q
Zebra Danio
Brachydanio rerio
NP_001032192
205
22276
L124
G
F
A
G
I
L
G
L
F
L
G
R
G
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783974
247
26909
K166
C
Y
P
Y
Q
A
V
K
I
G
K
A
E
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
91.4
74.8
N.A.
76.8
73.5
N.A.
42.1
55.5
44.5
28.3
N.A.
N.A.
N.A.
N.A.
33.2
Protein Similarity:
100
99.2
93.1
80
N.A.
86.5
83.2
N.A.
53.7
70.2
59.4
45.9
N.A.
N.A.
N.A.
N.A.
50.3
P-Site Identity:
100
100
93.3
73.3
N.A.
0
6.6
N.A.
6.6
46.6
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
46.6
13.3
N.A.
26.6
53.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
19
0
0
19
10
0
0
0
10
19
10
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
28
46
19
10
19
% E
% Phe:
10
10
0
10
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
10
0
10
10
10
0
10
0
0
10
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
10
10
0
0
10
19
0
0
0
0
10
0
% I
% Lys:
0
37
0
10
10
19
46
19
0
37
37
0
19
0
0
% K
% Leu:
10
0
0
46
0
10
10
10
0
10
0
0
0
37
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
10
0
0
0
10
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
37
% P
% Gln:
10
10
0
0
10
0
0
0
10
10
10
0
10
0
19
% Q
% Arg:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
10
% R
% Ser:
0
10
55
10
10
10
0
28
37
10
10
19
37
10
0
% S
% Thr:
0
0
0
0
0
37
0
10
10
10
0
0
0
10
0
% T
% Val:
46
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% V
% Trp:
10
0
0
0
55
0
10
10
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _