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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOOL
All Species:
4.55
Human Site:
S205
Identified Species:
10
UniProt:
Q6UXV4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXV4
NP_940852.3
268
29159
S205
K
T
K
L
G
S
S
S
E
I
E
V
P
A
K
Chimpanzee
Pan troglodytes
XP_521156
268
29148
S205
K
T
Q
L
G
S
S
S
E
I
E
V
P
A
K
Rhesus Macaque
Macaca mulatta
XP_001082461
279
30617
V216
K
T
K
L
G
S
S
V
E
I
E
V
P
A
K
Dog
Lupus familis
XP_850962
306
33240
A243
K
P
K
L
G
N
S
A
E
I
E
I
P
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q78IK4
265
29242
G202
P
K
E
E
S
K
E
G
R
S
D
E
I
H
A
Rat
Rattus norvegicus
NP_001014127
254
28219
R192
K
E
E
T
K
E
G
R
P
D
E
I
H
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517543
213
21966
P151
E
A
V
E
T
P
P
P
P
P
Q
V
L
L
R
Chicken
Gallus gallus
Q5ZK55
272
30116
K202
S
V
T
Q
E
N
K
K
N
R
E
I
S
N
V
Frog
Xenopus laevis
NP_001088003
301
33340
E204
K
V
P
V
S
V
T
E
G
D
H
H
Q
E
E
Zebra Danio
Brachydanio rerio
NP_001032192
205
22276
A143
I
Y
P
T
G
L
M
A
V
G
A
S
M
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783974
247
26909
G185
K
A
A
D
L
Y
K
G
A
T
S
T
P
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
91.4
74.8
N.A.
76.8
73.5
N.A.
42.1
55.5
44.5
28.3
N.A.
N.A.
N.A.
N.A.
33.2
Protein Similarity:
100
99.2
93.1
80
N.A.
86.5
83.2
N.A.
53.7
70.2
59.4
45.9
N.A.
N.A.
N.A.
N.A.
50.3
P-Site Identity:
100
93.3
93.3
73.3
N.A.
0
26.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
93.3
N.A.
13.3
40
N.A.
26.6
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
0
0
0
19
10
0
10
0
0
55
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
19
10
0
0
0
0
% D
% Glu:
10
10
19
19
10
10
10
10
37
0
55
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
46
0
10
19
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
10
10
10
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
37
0
28
10
0
0
% I
% Lys:
64
10
28
0
10
10
19
10
0
0
0
0
0
0
46
% K
% Leu:
0
0
0
37
10
10
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
19
0
0
10
0
0
0
0
10
0
% N
% Pro:
10
10
19
0
0
10
10
10
19
10
0
0
46
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
10
% R
% Ser:
10
0
0
0
19
28
37
19
0
10
10
10
10
0
0
% S
% Thr:
0
28
10
19
10
0
10
0
0
10
0
10
0
0
0
% T
% Val:
0
19
10
10
0
10
0
10
10
0
0
37
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _