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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSPO2 All Species: 28.48
Human Site: S36 Identified Species: 69.63
UniProt: Q6UXX9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UXX9 NP_848660.3 243 28315 S36 S K R A S Y V S N P I C K G C
Chimpanzee Pan troglodytes XP_001134914 243 28280 S36 S K R A S Y V S N P I C K G C
Rhesus Macaque Macaca mulatta XP_001089438 243 28262 S36 S K R V V Y V S N P I C K G C
Dog Lupus familis XP_539125 243 28150 S36 S K R A S Y V S N P I C K G C
Cat Felis silvestris
Mouse Mus musculus Q8BFU0 243 28257 S36 N K R A S Y V S N P I C K G C
Rat Rattus norvegicus NP_001124047 226 25713 S36 S K R A S Y V S N P I C K G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517935 235 25876 R36 Q K L F F F L R R E G M R Q Y
Chicken Gallus gallus XP_418383 230 25958 S36 C K G C L S C S K D N G C I R
Frog Xenopus laevis Q5UE90 243 27861 T36 S K R A S Y G T N P I C K G C
Zebra Danio Brachydanio rerio Q5R328 317 35924 S38 K Q V S G V S S Q G C Q G G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.9 97.5 N.A. 95.8 83.5 N.A. 68.7 74.9 83.9 40 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 97.9 98.3 N.A. 97.5 86.8 N.A. 74 81.8 91.7 53.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 100 N.A. 93.3 100 N.A. 6.6 13.3 86.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. 26.6 13.3 93.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 10 0 0 10 0 0 10 0 0 0 10 70 10 0 80 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 10 10 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 10 0 10 0 0 10 10 10 10 80 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 70 0 0 10 0 % I
% Lys: 10 90 0 0 0 0 0 0 10 0 0 0 70 0 0 % K
% Leu: 0 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 70 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 10 0 0 10 0 10 0 % Q
% Arg: 0 0 70 0 0 0 0 10 10 0 0 0 10 0 10 % R
% Ser: 60 0 0 10 60 10 10 80 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 10 10 10 10 60 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 70 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _