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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPO2
All Species:
26.97
Human Site:
Y34
Identified Species:
65.93
UniProt:
Q6UXX9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXX9
NP_848660.3
243
28315
Y34
R
R
S
K
R
A
S
Y
V
S
N
P
I
C
K
Chimpanzee
Pan troglodytes
XP_001134914
243
28280
Y34
R
R
S
K
R
A
S
Y
V
S
N
P
I
C
K
Rhesus Macaque
Macaca mulatta
XP_001089438
243
28262
Y34
R
R
S
K
R
V
V
Y
V
S
N
P
I
C
K
Dog
Lupus familis
XP_539125
243
28150
Y34
R
R
S
K
R
A
S
Y
V
S
N
P
I
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFU0
243
28257
Y34
R
R
N
K
R
A
S
Y
V
S
N
P
I
C
K
Rat
Rattus norvegicus
NP_001124047
226
25713
Y34
R
R
S
K
R
A
S
Y
V
S
N
P
I
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517935
235
25876
F34
C
Q
Q
K
L
F
F
F
L
R
R
E
G
M
R
Chicken
Gallus gallus
XP_418383
230
25958
S34
P
I
C
K
G
C
L
S
C
S
K
D
N
G
C
Frog
Xenopus laevis
Q5UE90
243
27861
Y34
R
R
S
K
R
A
S
Y
G
T
N
P
I
C
K
Zebra Danio
Brachydanio rerio
Q5R328
317
35924
V36
G
N
K
Q
V
S
G
V
S
S
Q
G
C
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
97.5
N.A.
95.8
83.5
N.A.
68.7
74.9
83.9
40
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.9
98.3
N.A.
97.5
86.8
N.A.
74
81.8
91.7
53.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
93.3
100
N.A.
6.6
13.3
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
33.3
13.3
93.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
10
0
0
10
0
0
10
0
0
0
10
70
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
10
0
10
0
0
10
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
70
0
0
% I
% Lys:
0
0
10
90
0
0
0
0
0
0
10
0
0
0
70
% K
% Leu:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
70
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% P
% Gln:
0
10
10
10
0
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
70
70
0
0
70
0
0
0
0
10
10
0
0
0
10
% R
% Ser:
0
0
60
0
0
10
60
10
10
80
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
10
10
10
10
60
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _