KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC5
All Species:
0.91
Human Site:
T884
Identified Species:
2.22
UniProt:
Q6UXY8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXY8
NP_001098718.1
1006
114770
T884
S
I
Y
S
W
I
D
T
L
S
H
R
P
G
Y
Chimpanzee
Pan troglodytes
XP_001153396
949
108074
I861
A
I
T
I
W
R
I
I
T
Y
L
Y
W
Q
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547109
928
106078
G840
L
F
F
P
S
F
T
G
V
L
C
T
L
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q32NZ6
967
111052
L874
H
F
F
F
I
L
T
L
I
V
L
I
I
T
Y
Rat
Rattus norvegicus
Q5M7W4
965
110699
L872
H
F
F
F
I
L
T
L
I
V
L
I
I
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509198
962
110947
P874
T
L
C
R
T
L
D
P
P
A
E
A
G
P
S
Chicken
Gallus gallus
Q5YCC5
735
84359
G647
T
I
L
E
F
P
I
G
L
Q
K
F
L
Y
G
Frog
Xenopus laevis
NP_001085652
725
84100
Y637
W
V
S
W
I
H
R
Y
L
V
E
N
T
F
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395471
756
87723
F668
L
I
V
T
F
A
E
F
P
D
W
L
Q
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783735
885
99854
N797
N
K
K
L
G
I
T
N
P
N
D
S
V
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
72.4
N.A.
73.2
73.4
N.A.
50.8
20.5
26.7
N.A.
N.A.
N.A.
21.4
N.A.
24
Protein Similarity:
100
92.8
N.A.
78.3
N.A.
80
80.9
N.A.
63.4
37
43
N.A.
N.A.
N.A.
37.9
N.A.
39.9
P-Site Identity:
100
13.3
N.A.
0
N.A.
6.6
6.6
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
20
N.A.
13.3
N.A.
26.6
26.6
N.A.
33.3
26.6
20
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
10
0
10
0
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
0
0
10
10
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
10
0
0
0
20
0
0
0
0
% E
% Phe:
0
30
30
20
20
10
0
10
0
0
0
10
0
10
20
% F
% Gly:
0
0
0
0
10
0
0
20
0
0
0
0
10
10
10
% G
% His:
20
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
40
0
10
30
20
20
10
20
0
0
20
20
0
30
% I
% Lys:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
20
10
10
10
0
30
0
20
30
10
30
10
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
30
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% Q
% Arg:
0
0
0
10
0
10
10
0
0
0
0
10
0
0
0
% R
% Ser:
10
0
10
10
10
0
0
0
0
10
0
10
0
10
10
% S
% Thr:
20
0
10
10
10
0
40
10
10
0
0
10
10
20
0
% T
% Val:
0
10
10
0
0
0
0
0
10
30
0
0
10
10
0
% V
% Trp:
10
0
0
10
20
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
10
0
10
0
10
30
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _