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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC5D
All Species:
25.15
Human Site:
Y580
Identified Species:
50.3
UniProt:
Q6UXZ4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXZ4
NP_543148.2
953
105880
Y580
E
E
N
S
W
E
I
Y
M
S
I
N
Q
G
E
Chimpanzee
Pan troglodytes
XP_001169461
948
105473
Y575
E
E
N
S
W
E
I
Y
M
S
I
N
Q
G
E
Rhesus Macaque
Macaca mulatta
XP_001088208
953
105918
Y580
E
E
N
S
W
E
I
Y
M
S
I
N
Q
G
E
Dog
Lupus familis
XP_539972
958
106821
Y585
E
E
N
S
W
E
I
Y
M
S
I
N
Q
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1S2
956
106334
Y583
E
E
N
S
W
E
I
Y
M
S
I
N
Q
G
E
Rat
Rattus norvegicus
O08722
945
103502
Y581
Q
G
K
F
Y
D
L
Y
L
R
I
N
K
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513625
621
68664
D266
D
Y
G
V
D
V
I
D
S
S
A
L
T
G
G
Chicken
Gallus gallus
Q7T2Z5
931
102888
V569
G
R
V
Y
E
M
Y
V
T
V
H
R
K
E
G
Frog
Xenopus laevis
Q8JGT4
943
105065
Y580
Q
G
K
Y
Y
E
M
Y
L
M
I
N
K
R
E
Zebra Danio
Brachydanio rerio
XP_001342230
936
103871
E576
Y
M
L
I
N
Q
G
E
T
S
A
Q
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95TU8
1072
116399
C700
L
L
L
L
S
D
E
C
S
R
V
S
C
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q26261
919
101607
T546
L
A
V
S
D
T
L
T
D
Q
P
H
L
K
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
99.3
95.3
N.A.
96.2
52.2
N.A.
59.1
50.2
51.3
65.2
N.A.
24.5
N.A.
25.5
N.A.
Protein Similarity:
100
97.5
99.4
96
N.A.
97.3
70
N.A.
61.7
67
70
79
N.A.
39.2
N.A.
42.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
20
0
33.3
13.3
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
26.6
6.6
66.6
20
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
17
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
17
17
0
9
9
0
0
0
0
0
0
% D
% Glu:
42
42
0
0
9
50
9
9
0
0
0
0
0
17
67
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
0
0
0
9
0
0
0
0
0
0
50
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
50
0
0
0
59
0
0
0
0
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
25
9
0
% K
% Leu:
17
9
17
9
0
0
17
0
17
0
0
9
9
0
0
% L
% Met:
0
9
0
0
0
9
9
0
42
9
0
0
0
0
0
% M
% Asn:
0
0
42
0
9
0
0
0
0
0
0
59
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% P
% Gln:
17
0
0
0
0
9
0
0
0
9
0
9
42
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
17
0
9
0
9
0
% R
% Ser:
0
0
0
50
9
0
0
0
17
59
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
9
17
0
0
0
9
9
9
% T
% Val:
0
0
17
9
0
9
0
9
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
17
17
0
9
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _