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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTSL4
All Species:
8.18
Human Site:
Y557
Identified Species:
22.5
UniProt:
Q6UY14
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UY14
NP_061905.2
1074
116545
Y557
A
G
G
T
V
F
R
Y
N
R
P
P
R
E
E
Chimpanzee
Pan troglodytes
XP_001169261
1074
116702
Y557
A
G
G
T
V
F
R
Y
N
R
P
P
R
E
E
Rhesus Macaque
Macaca mulatta
XP_001106147
1017
110435
V523
E
G
P
T
T
Q
P
V
D
V
Y
M
I
F
Q
Dog
Lupus familis
XP_540302
1085
118093
Y567
A
S
G
T
V
F
L
Y
N
R
P
S
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80T21
1036
113207
K530
R
P
P
R
E
E
G
K
G
E
S
L
S
A
E
Rat
Rattus norvegicus
Q4FZU4
1030
112766
G528
P
P
R
E
E
G
K
G
E
T
L
S
A
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413780
1008
112452
H515
V
L
D
V
Y
M
I
H
Q
Q
P
N
P
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684575
641
70986
G148
N
E
I
R
S
R
A
G
E
S
I
T
A
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198493
604
67300
C112
S
N
T
V
E
D
M
C
R
D
C
G
G
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92
81.5
N.A.
77
76.3
N.A.
N.A.
38
N.A.
25.4
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
100
99.3
92.5
85.9
N.A.
82.7
82.4
N.A.
N.A.
51.8
N.A.
36.9
N.A.
N.A.
N.A.
N.A.
31.6
P-Site Identity:
100
100
13.3
80
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
80
N.A.
6.6
13.3
N.A.
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
12
0
0
0
0
0
23
12
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
0
0
12
12
0
0
0
12
0
% D
% Glu:
12
12
0
12
34
12
0
0
23
12
0
0
0
45
45
% E
% Phe:
0
0
0
0
0
34
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
34
34
0
0
12
12
23
12
0
0
12
12
12
23
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
12
0
0
0
12
0
12
0
12
% I
% Lys:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
12
0
0
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
12
12
0
0
0
0
12
0
0
0
% M
% Asn:
12
12
0
0
0
0
0
0
34
0
0
12
0
0
12
% N
% Pro:
12
23
23
0
0
0
12
0
0
0
45
23
12
12
0
% P
% Gln:
0
0
0
0
0
12
0
0
12
12
0
0
0
0
12
% Q
% Arg:
12
0
12
23
0
12
23
0
12
34
0
0
34
0
0
% R
% Ser:
12
12
0
0
12
0
0
0
0
12
12
23
12
0
0
% S
% Thr:
0
0
12
45
12
0
0
0
0
12
0
12
0
0
0
% T
% Val:
12
0
0
23
34
0
0
12
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
34
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _