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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT4
All Species:
13.64
Human Site:
S2206
Identified Species:
30
UniProt:
Q6V0I7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6V0I7
NP_078858.4
4981
542687
S2206
N
Q
E
F
R
I
D
S
V
T
G
A
I
T
V
Chimpanzee
Pan troglodytes
XP_526682
4982
542612
S2206
N
Q
E
F
R
I
D
S
V
T
G
A
I
T
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_856760
3577
389736
G870
V
N
V
P
E
N
L
G
T
L
P
R
T
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q2PZL6
4981
540324
S2206
H
Q
E
F
R
I
D
S
V
T
G
A
I
T
V
Rat
Rattus norvegicus
Q8R508
4555
502069
F1848
E
V
I
A
H
F
H
F
H
V
H
V
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505705
1683
177151
Chicken
Gallus gallus
XP_420617
4932
535184
S2204
G
N
Q
F
R
I
D
S
V
T
G
V
I
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689394
2671
291199
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P33450
5147
564773
E2330
N
H
D
F
S
I
S
E
D
T
G
V
V
R
V
Honey Bee
Apis mellifera
XP_393497
5044
552460
S2260
E
N
A
S
I
G
A
S
V
L
Q
V
S
A
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785601
4811
518592
D2104
D
N
A
P
V
F
E
D
S
Y
A
P
S
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
68.8
N.A.
91.4
26.6
N.A.
20.9
81
N.A.
39.2
N.A.
36.2
37
N.A.
36.1
Protein Similarity:
100
99.8
N.A.
70.6
N.A.
96
43.9
N.A.
27.2
89.9
N.A.
45.9
N.A.
53.5
54.1
N.A.
54.1
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
0
N.A.
0
73.3
N.A.
0
N.A.
40
13.3
N.A.
0
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
0
N.A.
0
80
N.A.
0
N.A.
53.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
0
0
10
0
0
0
10
28
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
37
10
10
0
0
0
0
10
0
% D
% Glu:
19
0
28
0
10
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
46
0
19
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
10
0
0
46
0
0
0
0
% G
% His:
10
10
0
0
10
0
10
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
10
46
0
0
0
0
0
0
37
19
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
19
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
28
37
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
19
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
28
10
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
37
0
0
0
0
0
0
10
10
10
0
% R
% Ser:
0
0
0
10
10
0
10
46
10
0
0
0
19
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
46
0
0
10
37
0
% T
% Val:
10
10
10
0
10
0
0
0
46
10
0
37
10
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _