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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT4 All Species: 9.39
Human Site: S4865 Identified Species: 20.67
UniProt: Q6V0I7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6V0I7 NP_078858.4 4981 542687 S4865 E K P M V Y T S R M P K L S Q
Chimpanzee Pan troglodytes XP_526682 4982 542612 S4866 E K P M V Y T S R M P K L S Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_856760 3577 389736 M3463 P M V Y T S R M P K L S Q V N
Cat Felis silvestris
Mouse Mus musculus Q2PZL6 4981 540324 S4867 E K P V V Y T S R M P K L S Q
Rat Rattus norvegicus Q8R508 4555 502069 T4441 P S Q P T S L T G T M S P D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505705 1683 177151 P1569 F K S R E S P P V I L V A N E
Chicken Gallus gallus XP_420617 4932 535184 M4814 P I A Y T S R M P K L S Q V N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689394 2671 291199 P2557 V S Y S S R M P K L S Q V N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P33450 5147 564773 A5019 G R S P V S R A L S G G E T S
Honey Bee Apis mellifera XP_393497 5044 552460 Q4924 S D N P F A K Q D D E E V N Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785601 4811 518592 E4697 T C S E M D S E Y G K H G G F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 68.8 N.A. 91.4 26.6 N.A. 20.9 81 N.A. 39.2 N.A. 36.2 37 N.A. 36.1
Protein Similarity: 100 99.8 N.A. 70.6 N.A. 96 43.9 N.A. 27.2 89.9 N.A. 45.9 N.A. 53.5 54.1 N.A. 54.1
P-Site Identity: 100 100 N.A. 0 N.A. 93.3 0 N.A. 6.6 0 N.A. 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 0 N.A. 100 6.6 N.A. 26.6 0 N.A. 40 N.A. 26.6 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 10 0 0 0 0 10 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 0 0 0 10 0 0 10 10 0 0 0 10 0 % D
% Glu: 28 0 0 10 10 0 0 10 0 0 10 10 10 0 19 % E
% Phe: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 0 0 0 0 0 0 10 10 10 10 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 37 0 0 0 0 10 0 10 19 10 28 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 10 10 28 0 28 0 0 % L
% Met: 0 10 0 19 10 0 10 19 0 28 10 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 28 19 % N
% Pro: 28 0 28 28 0 0 10 19 19 0 28 0 10 0 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 10 19 0 37 % Q
% Arg: 0 10 0 10 0 10 28 0 28 0 0 0 0 0 0 % R
% Ser: 10 19 28 10 10 46 10 28 0 10 10 28 0 28 10 % S
% Thr: 10 0 0 0 28 0 28 10 0 10 0 0 0 10 0 % T
% Val: 10 0 10 10 37 0 0 0 10 0 0 10 19 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 19 0 28 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _