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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCHS2 All Species: 16.97
Human Site: Y2777 Identified Species: 37.33
UniProt: Q6V1P9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6V1P9 NP_001136024.1 2916 322234 Y2777 D H D G K D N Y H W N Y L L S
Chimpanzee Pan troglodytes XP_526708 2852 314857 Y2713 D H D G K G N Y H W N Y L L S
Rhesus Macaque Macaca mulatta XP_001100797 3386 356115 Y3249 E E E L R G S Y N W D Y L L S
Dog Lupus familis XP_539776 2322 253044 A2211 S H Q H V P E A P E I W Q Q H
Cat Felis silvestris
Mouse Mus musculus Q2PZL6 4981 540324 C3852 L Q P S Q C K C V P G Y A G S
Rat Rattus norvegicus P58365 3317 365436 E3181 E P A A V K P E D D R Y L R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417264 2641 284628 E2530 E P A L P G A E H I Y H Q A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001343759 3189 349215 M3073 S V F T D I G M L P D E G M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24292 3503 379762 Y3330 E E E L T G S Y N W D Y L L D
Honey Bee Apis mellifera XP_392300 3377 363497 Y3241 E E E L T G S Y N W D Y L L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785445 3342 362092 Y3176 D E E L S G S Y N W D Y L L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 29.1 21.5 N.A. 21.1 25.4 N.A. N.A. 23.4 N.A. 34.3 N.A. 27.4 25.4 N.A. 27.8
Protein Similarity: 100 97 45.4 38.2 N.A. 35 42.2 N.A. N.A. 40.9 N.A. 52.2 N.A. 45 42.5 N.A. 46.5
P-Site Identity: 100 93.3 40 6.6 N.A. 13.3 13.3 N.A. N.A. 6.6 N.A. 0 N.A. 33.3 33.3 N.A. 40
P-Site Similarity: 100 93.3 80 13.3 N.A. 20 26.6 N.A. N.A. 20 N.A. 13.3 N.A. 66.6 66.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 10 0 0 10 10 0 0 0 0 10 10 10 % A
% Cys: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % C
% Asp: 28 0 19 0 10 10 0 0 10 10 46 0 0 0 28 % D
% Glu: 46 37 37 0 0 0 10 19 0 10 0 10 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 19 0 55 10 0 0 0 10 0 10 10 0 % G
% His: 0 28 0 10 0 0 0 0 28 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 0 0 19 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 46 0 0 0 0 10 0 0 0 64 55 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 19 0 37 0 19 0 0 0 0 % N
% Pro: 0 19 10 0 10 10 10 0 10 19 0 0 0 0 0 % P
% Gln: 0 10 10 0 10 0 0 0 0 0 0 0 19 10 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 10 0 0 10 10 % R
% Ser: 19 0 0 10 10 0 37 0 0 0 0 0 0 0 37 % S
% Thr: 0 0 0 10 19 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 19 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 55 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 0 0 10 73 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _