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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPP8 All Species: 21.52
Human Site: T250 Identified Species: 43.03
UniProt: Q6V1X1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6V1X1 NP_060213.2 898 103358 T250 T R E E R R L T Y V H N E L A
Chimpanzee Pan troglodytes Q5IS50 803 91393 P187 L Q Y A G W G P K G Q Q L I F
Rhesus Macaque Macaca mulatta XP_001109572 891 102400 T243 T R E E R R L T Y V H N E L A
Dog Lupus familis XP_852538 891 102380 T243 T R E E R R L T Y V H N E L A
Cat Felis silvestris
Mouse Mus musculus Q80YA7 892 102167 T244 T R E E R R I T Y V H N E L A
Rat Rattus norvegicus P14740 767 88070 Q151 E K I P N N T Q W I T W S Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506717 790 90374 G174 E E F D R Y S G Y W W C P K A
Chicken Gallus gallus XP_425086 882 101282 F235 R E E R R L T F V H N E L A N
Frog Xenopus laevis NP_001128703 888 101057 T235 T G D E R R L T F V H K D L A
Zebra Danio Brachydanio rerio NP_001070781 885 101262 T247 T A E E R R L T F C H K G L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q7JKY3 799 91347 S183 I G L R K E E S V I Q A F K W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P18962 818 93386 A202 S P N S N D I A Y V Q D N N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.1 98.7 98 N.A. 94.9 24.5 N.A. 80 87.7 77.7 59 N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: 100 39.8 99 98.8 N.A. 97 39.8 N.A. 84.4 93.7 86.8 76.5 N.A. N.A. N.A. 37.7 N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 0 N.A. 20 13.3 66.6 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 20 N.A. 26.6 20 86.6 66.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 9 0 0 0 9 0 9 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % C
% Asp: 0 0 9 9 0 9 0 0 0 0 0 9 9 0 0 % D
% Glu: 17 17 50 50 0 9 9 0 0 0 0 9 34 0 9 % E
% Phe: 0 0 9 0 0 0 0 9 17 0 0 0 9 0 9 % F
% Gly: 0 17 0 0 9 0 9 9 0 9 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 50 0 0 0 0 % H
% Ile: 9 0 9 0 0 0 17 0 0 17 0 0 0 9 9 % I
% Lys: 0 9 0 0 9 0 0 0 9 0 0 17 0 17 0 % K
% Leu: 9 0 9 0 0 9 42 0 0 0 0 0 17 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 17 9 0 0 0 0 9 34 9 9 17 % N
% Pro: 0 9 0 9 0 0 0 9 0 0 0 0 9 0 0 % P
% Gln: 0 9 0 0 0 0 0 9 0 0 25 9 0 9 0 % Q
% Arg: 9 34 0 17 67 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 9 0 0 9 9 0 0 0 0 9 0 0 % S
% Thr: 50 0 0 0 0 0 17 50 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 17 50 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 9 9 9 9 0 0 9 % W
% Tyr: 0 0 9 0 0 9 0 0 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _