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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2R1
All Species:
20.91
Human Site:
S293
Identified Species:
57.5
UniProt:
Q6VVX0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VVX0
NP_078790.2
501
57359
S293
Q
G
K
N
D
P
S
S
T
F
S
K
E
N
L
Chimpanzee
Pan troglodytes
Q2XNC8
497
55843
S288
K
A
K
G
N
P
E
S
S
F
N
D
E
N
L
Rhesus Macaque
Macaca mulatta
XP_001092782
501
57156
S293
Q
G
K
N
D
P
S
S
T
F
S
K
E
N
L
Dog
Lupus familis
XP_854533
501
56672
C293
Q
G
K
N
D
P
S
C
T
F
S
K
E
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6VVW9
501
57295
S293
Q
G
Q
N
D
P
L
S
T
F
S
K
E
N
L
Rat
Rattus norvegicus
Q4V8D1
530
60381
T321
E
K
D
K
C
K
G
T
N
F
D
E
D
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518489
432
49466
L238
L
I
F
A
L
G
E
L
I
I
A
G
T
E
T
Chicken
Gallus gallus
XP_420996
646
71804
S438
C
N
K
N
D
P
E
S
T
Y
S
R
E
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691824
506
58485
T297
Q
S
T
P
D
K
A
T
S
F
S
Q
D
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.1
97.4
93.2
N.A.
88.6
38.2
N.A.
60
63.7
N.A.
67
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
98.4
95
N.A.
93.2
57.5
N.A.
72.4
69.9
N.A.
80.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
93.3
N.A.
86.6
13.3
N.A.
0
66.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
93.3
N.A.
93.3
40
N.A.
6.6
80
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
0
0
12
0
0
0
12
0
0
0
0
% A
% Cys:
12
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
67
0
0
0
0
0
12
12
23
0
0
% D
% Glu:
12
0
0
0
0
0
34
0
0
0
0
12
67
12
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
78
0
0
0
0
0
% F
% Gly:
0
45
0
12
0
12
12
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
12
12
0
0
0
0
0
% I
% Lys:
12
12
56
12
0
23
0
0
0
0
0
45
0
0
0
% K
% Leu:
12
0
0
0
12
0
12
12
0
0
0
0
0
0
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
56
12
0
0
0
12
0
12
0
0
78
0
% N
% Pro:
0
0
0
12
0
67
0
0
0
0
0
0
0
0
0
% P
% Gln:
56
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
12
0
0
0
0
34
56
23
0
67
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
23
56
0
0
0
12
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _