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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2R1
All Species:
13.33
Human Site:
Y431
Identified Species:
36.67
UniProt:
Q6VVX0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VVX0
NP_078790.2
501
57359
Y431
R
F
L
D
S
S
G
Y
F
A
K
K
E
A
L
Chimpanzee
Pan troglodytes
Q2XNC8
497
55843
H426
H
F
L
D
A
Q
G
H
F
V
K
P
E
A
F
Rhesus Macaque
Macaca mulatta
XP_001092782
501
57156
Y431
R
F
L
D
S
S
G
Y
F
A
K
K
E
A
L
Dog
Lupus familis
XP_854533
501
56672
Y431
R
F
L
D
S
S
G
Y
F
A
K
K
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6VVW9
501
57295
Y431
R
F
L
D
S
N
G
Y
F
T
K
K
E
A
L
Rat
Rattus norvegicus
Q4V8D1
530
60381
Q459
R
F
L
D
D
Q
G
Q
L
L
K
R
E
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518489
432
49466
Q362
R
F
L
D
S
R
G
Q
F
V
K
N
E
A
L
Chicken
Gallus gallus
XP_420996
646
71804
Q576
R
F
L
D
S
N
G
Q
F
V
K
K
D
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691824
506
58485
K434
R
F
L
D
C
N
G
K
F
I
R
H
E
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.1
97.4
93.2
N.A.
88.6
38.2
N.A.
60
63.7
N.A.
67
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
98.4
95
N.A.
93.2
57.5
N.A.
72.4
69.9
N.A.
80.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
86.6
46.6
N.A.
73.3
66.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
93.3
53.3
N.A.
73.3
80
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
34
0
0
0
89
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
12
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
89
0
0
% E
% Phe:
0
100
0
0
0
0
0
0
89
0
0
0
0
0
45
% F
% Gly:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
89
56
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
12
12
0
0
0
0
56
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
34
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
23
0
34
0
0
0
0
0
0
0
% Q
% Arg:
89
0
0
0
0
12
0
0
0
0
12
12
0
0
0
% R
% Ser:
0
0
0
0
67
34
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _