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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
19.7
Human Site:
S442
Identified Species:
36.11
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S442
A
A
L
E
K
I
K
S
T
W
I
K
N
Q
D
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S442
A
A
L
E
K
I
K
S
T
W
I
K
N
Q
D
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S441
A
A
L
E
K
F
K
S
T
W
I
K
N
Q
D
Dog
Lupus familis
XP_540837
888
97890
D374
S
A
W
I
K
N
Q
D
D
S
L
T
E
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S440
A
A
L
E
K
V
K
S
T
W
I
K
N
Q
D
Rat
Rattus norvegicus
O88588
961
104682
S440
A
A
L
E
K
V
K
S
T
W
I
K
N
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_419325
859
94655
Q345
K
P
G
A
P
R
A
Q
E
E
P
G
A
E
E
Frog
Xenopus laevis
NP_001124414
878
97767
C364
G
P
K
P
P
S
D
C
V
S
D
T
V
S
L
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
L395
A
F
S
D
V
D
P
L
E
F
N
E
V
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
R576
D
P
Q
N
S
P
P
R
D
K
D
Y
L
R
L
Honey Bee
Apis mellifera
XP_001120982
812
90475
T298
D
S
G
P
E
L
D
T
M
S
V
S
S
T
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
E203
N
D
L
L
G
E
G
E
E
E
H
E
P
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
93.3
20
N.A.
93.3
93.3
N.A.
0
0
0
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
40
N.A.
100
100
N.A.
0
13.3
0
33.3
N.A.
6.6
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
47
0
8
0
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
16
8
0
8
0
8
16
8
16
0
16
0
0
0
47
% D
% Glu:
0
0
0
39
8
8
0
8
24
16
0
16
8
16
8
% E
% Phe:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
16
0
8
0
8
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
16
0
0
0
0
39
0
0
0
0
% I
% Lys:
8
0
8
0
47
0
39
0
0
8
0
39
0
0
0
% K
% Leu:
0
0
47
8
0
8
0
8
0
0
8
0
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
8
0
0
0
0
8
0
39
0
0
% N
% Pro:
0
24
0
16
16
8
16
0
0
0
8
0
8
0
8
% P
% Gln:
0
0
8
0
0
0
8
8
0
0
0
0
0
39
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
8
% R
% Ser:
8
8
8
0
8
8
0
39
0
24
0
8
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
39
0
0
16
0
16
0
% T
% Val:
0
0
0
0
8
16
0
0
8
0
8
0
16
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
39
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _