KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
18.18
Human Site:
S451
Identified Species:
33.33
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S451
W
I
K
N
Q
D
D
S
L
T
E
T
D
T
L
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S451
W
I
K
N
Q
D
D
S
L
T
E
T
D
T
L
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S450
W
I
K
N
Q
D
D
S
L
T
E
T
D
T
L
Dog
Lupus familis
XP_540837
888
97890
L383
S
L
T
E
T
D
T
L
E
I
T
D
Q
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S449
W
I
K
N
Q
D
D
S
L
T
E
T
D
T
L
Rat
Rattus norvegicus
O88588
961
104682
S449
W
I
K
N
Q
D
D
S
L
T
E
T
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
G12
L
R
A
L
T
F
S
G
I
E
S
L
R
P
I
Chicken
Gallus gallus
XP_419325
859
94655
C354
E
P
G
A
E
E
P
C
P
R
L
A
P
P
E
Frog
Xenopus laevis
NP_001124414
878
97767
A373
S
D
T
V
S
L
E
A
P
Q
Q
E
A
Q
D
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
A404
F
N
E
V
E
V
I
A
D
G
T
P
S
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
Q585
K
D
Y
L
R
L
Q
Q
M
Q
Q
Q
Q
L
T
Honey Bee
Apis mellifera
XP_001120982
812
90475
P307
S
V
S
S
T
P
K
P
S
L
R
P
F
F
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
G212
E
H
E
P
G
R
K
G
N
K
I
H
N
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
0
0
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
13.3
13.3
20
26.6
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
16
0
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
47
39
0
8
0
0
8
39
8
8
% D
% Glu:
16
0
16
8
16
8
8
0
8
8
39
8
0
0
8
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
8
0
8
0
0
16
0
8
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
39
0
0
0
0
8
0
8
8
8
0
0
8
8
% I
% Lys:
8
0
39
0
0
0
16
0
0
8
0
0
0
0
0
% K
% Leu:
8
8
0
16
0
16
0
8
39
8
8
8
0
8
39
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
8
0
39
0
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
8
0
8
0
8
8
8
16
0
0
16
8
16
0
% P
% Gln:
0
0
0
0
39
0
8
8
0
16
16
8
16
8
0
% Q
% Arg:
0
8
0
0
8
8
0
0
0
8
8
0
8
0
0
% R
% Ser:
24
0
8
8
8
0
8
39
8
0
8
0
8
0
8
% S
% Thr:
0
0
16
0
24
0
8
0
0
39
16
39
0
39
24
% T
% Val:
0
8
0
16
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _