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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
20.61
Human Site:
S785
Identified Species:
37.78
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S785
P
S
T
S
P
P
S
S
S
G
L
S
R
D
A
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S785
P
S
T
S
P
P
S
S
S
G
L
S
R
D
A
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S784
P
S
T
S
P
P
S
S
S
G
L
S
R
D
A
Dog
Lupus familis
XP_540837
888
97890
S714
P
P
S
S
S
G
L
S
R
D
T
T
A
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S783
P
S
T
S
P
P
S
S
S
G
L
S
R
D
A
Rat
Rattus norvegicus
O88588
961
104682
S783
P
S
T
S
P
P
S
S
S
G
L
S
R
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
P343
L
I
S
D
D
Q
L
P
E
N
I
I
L
V
N
Chicken
Gallus gallus
XP_419325
859
94655
G685
L
S
S
V
P
A
A
G
S
A
S
P
Y
G
K
Frog
Xenopus laevis
NP_001124414
878
97767
V704
P
P
S
V
S
P
A
V
K
E
A
S
P
T
P
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
D735
S
P
T
G
M
M
K
D
S
A
T
P
P
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
Q979
G
R
I
S
P
P
L
Q
T
P
P
S
S
A
S
Honey Bee
Apis mellifera
XP_001120982
812
90475
S638
S
N
V
T
M
S
G
S
P
P
S
L
P
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
G543
C
G
S
D
S
Y
I
G
S
V
L
K
P
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
20
N.A.
100
100
N.A.
0
20
20
13.3
N.A.
26.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
13.3
33.3
33.3
20
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
16
0
0
16
8
0
8
8
39
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
0
0
8
0
8
0
0
0
39
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
8
8
16
0
39
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
8
0
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
8
% K
% Leu:
16
0
0
0
0
0
24
0
0
0
47
8
8
0
0
% L
% Met:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
54
24
0
0
54
54
0
8
8
16
8
16
31
16
24
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
0
39
0
0
% R
% Ser:
16
47
39
54
24
8
39
54
62
0
16
54
8
0
16
% S
% Thr:
0
0
47
8
0
0
0
0
8
0
16
8
0
16
0
% T
% Val:
0
0
8
16
0
0
0
8
0
8
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _