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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
23.64
Human Site:
S859
Identified Species:
43.33
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S859
V
F
R
S
V
Q
V
S
R
L
P
H
S
G
E
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S859
V
F
R
S
V
Q
V
S
R
L
P
H
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S858
V
F
R
S
V
Q
V
S
R
L
P
H
S
G
E
Dog
Lupus familis
XP_540837
888
97890
R785
F
R
S
V
Q
V
S
R
L
P
H
G
G
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S857
V
F
R
S
V
Q
V
S
R
L
P
H
A
G
E
Rat
Rattus norvegicus
O88588
961
104682
S857
V
F
R
S
V
Q
V
S
R
L
P
H
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Y414
A
V
A
G
A
Q
N
Y
L
S
A
V
L
R
L
Chicken
Gallus gallus
XP_419325
859
94655
V756
S
N
F
R
S
L
Q
V
S
R
I
P
G
V
G
Frog
Xenopus laevis
NP_001124414
878
97767
S775
T
F
R
S
L
Q
V
S
R
L
P
S
N
T
D
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
S806
S
L
Q
V
S
R
L
S
S
S
S
S
T
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
L1066
R
N
L
Q
V
W
R
L
P
Q
H
A
Q
Q
L
Honey Bee
Apis mellifera
XP_001120982
812
90475
H709
H
V
Q
R
L
P
P
H
G
E
T
P
G
H
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
I614
A
A
G
D
K
R
E
I
A
N
R
V
E
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
6.6
0
60
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
0
N.A.
100
100
N.A.
6.6
0
80
33.3
N.A.
6.6
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
8
0
0
0
8
0
8
8
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
8
0
0
8
0
0
8
16
39
% E
% Phe:
8
47
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
8
0
0
8
24
39
8
% G
% His:
8
0
0
0
0
0
0
8
0
0
16
39
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
8
8
0
16
8
8
8
16
47
0
0
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
0
0
0
0
8
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
8
8
47
16
0
0
0
% P
% Gln:
0
0
16
8
8
54
8
0
0
8
0
0
8
8
0
% Q
% Arg:
8
8
47
16
0
16
8
8
47
8
8
0
0
8
0
% R
% Ser:
16
0
8
47
16
0
8
54
16
16
8
16
24
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
8
8
8
% T
% Val:
39
16
0
16
47
8
47
8
0
0
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _