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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
19.7
Human Site:
S870
Identified Species:
36.11
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S870
H
S
G
E
A
Q
L
S
G
T
M
A
M
T
V
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S870
H
S
G
E
A
Q
L
S
G
T
M
A
M
T
V
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S869
H
S
G
E
A
Q
L
S
G
T
M
A
M
T
V
Dog
Lupus familis
XP_540837
888
97890
G796
G
G
E
A
Q
L
S
G
T
M
A
M
T
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S868
H
A
G
E
A
Q
L
S
G
T
M
A
M
T
V
Rat
Rattus norvegicus
O88588
961
104682
S868
H
A
G
E
A
Q
L
S
G
T
M
A
M
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Q425
V
L
R
L
F
V
D
Q
L
S
H
R
T
P
D
Chicken
Gallus gallus
XP_419325
859
94655
P767
P
G
V
G
E
L
V
P
P
S
T
M
A
M
T
Frog
Xenopus laevis
NP_001124414
878
97767
A786
S
N
T
D
V
P
T
A
P
I
M
S
M
T
V
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
T817
S
T
E
T
G
F
N
T
M
S
M
T
V
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
F1077
A
Q
Q
L
G
D
M
F
N
G
L
T
V
S
F
Honey Bee
Apis mellifera
XP_001120982
812
90475
N720
P
G
H
Y
L
S
M
N
Y
T
T
K
E
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
A625
V
E
K
Y
L
S
G
A
T
T
S
L
G
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
0
0
26.6
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
6.6
13.3
53.3
33.3
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
39
0
0
16
0
0
8
39
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
16
39
8
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
8
% F
% Gly:
8
24
39
8
16
0
8
8
39
8
0
0
8
0
0
% G
% His:
39
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
8
% K
% Leu:
0
8
0
16
16
16
39
0
8
0
8
8
0
8
0
% L
% Met:
0
0
0
0
0
0
16
0
8
8
54
16
47
8
0
% M
% Asn:
0
8
0
0
0
0
8
8
8
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
0
8
0
8
16
0
0
0
0
8
8
% P
% Gln:
0
8
8
0
8
39
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
16
24
0
0
0
16
8
39
0
24
8
8
0
8
0
% S
% Thr:
0
8
8
8
0
0
8
8
16
54
16
16
16
47
16
% T
% Val:
16
0
8
0
8
8
8
0
0
0
0
0
16
16
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _