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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPSR1
All Species:
25.45
Human Site:
S259
Identified Species:
46.67
UniProt:
Q6W5P4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6W5P4
NP_997055.1
371
42687
S259
S
D
G
K
L
C
S
S
Y
N
R
G
L
I
S
Chimpanzee
Pan troglodytes
XP_001168820
371
42711
S259
S
D
G
K
L
C
S
S
Y
N
R
G
L
I
S
Rhesus Macaque
Macaca mulatta
Q56H79
371
42612
S259
S
D
G
K
L
C
S
S
Y
N
R
G
L
I
S
Dog
Lupus familis
XP_539511
374
42921
S262
S
G
G
K
L
C
T
S
Y
N
R
G
L
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZP8
371
42420
S259
S
D
G
K
L
C
C
S
Y
N
R
G
L
I
S
Rat
Rattus norvegicus
P0C0L6
372
42620
S260
S
D
G
E
L
C
C
S
Y
N
R
G
L
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519137
132
15251
F20
I
W
R
L
T
G
D
F
M
A
P
D
L
V
C
Chicken
Gallus gallus
XP_426022
373
42686
Y260
D
G
K
T
S
A
G
Y
T
S
R
G
F
I
S
Frog
Xenopus laevis
P70031
453
51139
S285
K
A
H
K
N
G
V
S
T
P
T
T
I
P
S
Zebra Danio
Brachydanio rerio
XP_001341507
388
44497
V258
K
G
N
A
L
A
R
V
S
S
V
K
L
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868T3
506
55785
A334
G
A
A
P
A
R
R
A
S
S
R
G
I
I
P
Honey Bee
Apis mellifera
XP_001122652
353
39441
L242
S
P
Y
I
V
F
D
L
L
Q
V
F
G
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784373
461
51252
S265
V
K
N
G
G
H
H
S
S
S
V
A
T
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97
88.2
N.A.
89.2
88.9
N.A.
31
73.9
22.5
30.4
N.A.
31.6
35
N.A.
27.5
Protein Similarity:
100
99.4
98.6
93.8
N.A.
94.3
94.6
N.A.
34.5
86.3
40.4
50
N.A.
47.8
54.4
N.A.
45.1
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
6.6
26.6
20
26.6
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
33.3
26.6
33.3
N.A.
40
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
8
16
0
8
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
47
16
0
0
0
0
0
0
0
8
% C
% Asp:
8
39
0
0
0
0
16
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
8
8
0
0
% F
% Gly:
8
24
47
8
8
16
8
0
0
0
0
62
8
0
0
% G
% His:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
0
16
70
0
% I
% Lys:
16
8
8
47
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
8
54
0
0
8
8
0
0
0
62
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
8
0
0
0
0
47
0
0
0
0
8
% N
% Pro:
0
8
0
8
0
0
0
0
0
8
8
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
16
0
0
0
62
0
0
0
0
% R
% Ser:
54
0
0
0
8
0
24
62
24
31
0
0
0
0
70
% S
% Thr:
0
0
0
8
8
0
8
0
16
0
8
8
8
8
0
% T
% Val:
8
0
0
0
8
0
8
8
0
0
24
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
47
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _