KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPSR1
All Species:
24.55
Human Site:
S346
Identified Species:
45
UniProt:
Q6W5P4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6W5P4
NP_997055.1
371
42687
S346
F
P
C
R
E
Q
R
S
Q
D
S
R
M
T
F
Chimpanzee
Pan troglodytes
XP_001168820
371
42711
S346
F
P
C
R
E
R
R
S
Q
D
S
R
M
T
F
Rhesus Macaque
Macaca mulatta
Q56H79
371
42612
S346
F
P
C
G
E
R
R
S
Q
D
S
I
M
T
F
Dog
Lupus familis
XP_539511
374
42921
S349
F
P
C
R
E
Q
T
S
R
G
S
R
K
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZP8
371
42420
S346
S
P
C
K
M
Q
R
S
Q
D
S
R
M
T
Y
Rat
Rattus norvegicus
P0C0L6
372
42620
S347
S
P
C
K
V
Q
R
S
Q
D
S
R
M
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519137
132
15251
W107
E
V
Q
C
W
A
L
W
P
D
E
S
Y
W
L
Chicken
Gallus gallus
XP_426022
373
42686
T347
T
P
F
E
E
R
R
T
R
R
L
E
G
T
F
Frog
Xenopus laevis
P70031
453
51139
S372
W
K
A
F
D
E
L
S
A
F
N
T
L
T
G
Zebra Danio
Brachydanio rerio
XP_001341507
388
44497
C345
L
K
Q
N
L
F
C
C
S
T
L
Y
L
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868T3
506
55785
P421
R
T
L
S
R
F
P
P
F
K
W
F
T
C
C
Honey Bee
Apis mellifera
XP_001122652
353
39441
Q329
V
T
T
S
L
T
A
Q
S
S
R
R
S
G
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784373
461
51252
D352
S
S
A
P
F
H
G
D
A
F
T
I
I
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97
88.2
N.A.
89.2
88.9
N.A.
31
73.9
22.5
30.4
N.A.
31.6
35
N.A.
27.5
Protein Similarity:
100
99.4
98.6
93.8
N.A.
94.3
94.6
N.A.
34.5
86.3
40.4
50
N.A.
47.8
54.4
N.A.
45.1
P-Site Identity:
100
93.3
80
73.3
N.A.
73.3
73.3
N.A.
6.6
33.3
13.3
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
86.6
80
N.A.
86.6
86.6
N.A.
6.6
53.3
46.6
6.6
N.A.
0
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
8
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
47
8
0
0
8
8
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
0
8
0
0
8
0
47
0
0
0
0
0
% D
% Glu:
8
0
0
8
39
8
0
0
0
0
8
8
0
0
0
% E
% Phe:
31
0
8
8
8
16
0
0
8
16
0
8
0
0
39
% F
% Gly:
0
0
0
8
0
0
8
0
0
8
0
0
8
8
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
16
8
0
0
% I
% Lys:
0
16
0
16
0
0
0
0
0
8
0
0
8
8
0
% K
% Leu:
8
0
8
0
16
0
16
0
0
0
16
0
16
0
16
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
39
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
54
0
8
0
0
8
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
0
31
0
8
39
0
0
0
0
0
0
% Q
% Arg:
8
0
0
24
8
24
47
0
16
8
8
47
0
0
0
% R
% Ser:
24
8
0
16
0
0
0
54
16
8
47
8
8
0
8
% S
% Thr:
8
16
8
0
0
8
8
8
0
8
8
8
8
62
0
% T
% Val:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
8
0
0
8
0
0
8
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _