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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPSR1 All Species: 26.06
Human Site: T352 Identified Species: 47.78
UniProt: Q6W5P4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6W5P4 NP_997055.1 371 42687 T352 R S Q D S R M T F R E R T E R
Chimpanzee Pan troglodytes XP_001168820 371 42711 T352 R S Q D S R M T F R E R T E R
Rhesus Macaque Macaca mulatta Q56H79 371 42612 T352 R S Q D S I M T F R E R T E R
Dog Lupus familis XP_539511 374 42921 T355 T S R G S R K T F R E R T Q R
Cat Felis silvestris
Mouse Mus musculus Q8BZP8 371 42420 T352 R S Q D S R M T Y R E R S E R
Rat Rattus norvegicus P0C0L6 372 42620 T353 R S Q D S R M T Y R E R S E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519137 132 15251 W113 L W P D E S Y W L P Y M M V V
Chicken Gallus gallus XP_426022 373 42686 T353 R T R R L E G T F R D R S D G
Frog Xenopus laevis P70031 453 51139 T378 L S A F N T L T G A P I S F I
Zebra Danio Brachydanio rerio XP_001341507 388 44497 K351 C C S T L Y L K S S Q C R Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q868T3 506 55785 C427 P P F K W F T C C C K S Y R N
Honey Bee Apis mellifera XP_001122652 353 39441 G335 A Q S S R R S G H I A M L H S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784373 461 51252 M358 G D A F T I I M L L A N L N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97 88.2 N.A. 89.2 88.9 N.A. 31 73.9 22.5 30.4 N.A. 31.6 35 N.A. 27.5
Protein Similarity: 100 99.4 98.6 93.8 N.A. 94.3 94.6 N.A. 34.5 86.3 40.4 50 N.A. 47.8 54.4 N.A. 45.1
P-Site Identity: 100 100 93.3 66.6 N.A. 86.6 86.6 N.A. 6.6 33.3 13.3 0 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 93.3 80 N.A. 100 100 N.A. 6.6 66.6 33.3 13.3 N.A. 6.6 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 0 0 0 0 8 16 0 0 0 0 % A
% Cys: 8 8 0 0 0 0 0 8 8 8 0 8 0 0 0 % C
% Asp: 0 8 0 47 0 0 0 0 0 0 8 0 0 8 8 % D
% Glu: 0 0 0 0 8 8 0 0 0 0 47 0 0 39 0 % E
% Phe: 0 0 8 16 0 8 0 0 39 0 0 0 0 8 0 % F
% Gly: 8 0 0 8 0 0 8 8 8 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 16 8 0 0 8 0 8 0 0 8 % I
% Lys: 0 0 0 8 0 0 8 8 0 0 8 0 0 0 0 % K
% Leu: 16 0 0 0 16 0 16 0 16 8 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 39 8 0 0 0 16 8 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 8 0 8 8 % N
% Pro: 8 8 8 0 0 0 0 0 0 8 8 0 0 0 0 % P
% Gln: 0 8 39 0 0 0 0 0 0 0 8 0 0 8 0 % Q
% Arg: 47 0 16 8 8 47 0 0 0 54 0 54 8 8 47 % R
% Ser: 0 54 16 8 47 8 8 0 8 8 0 8 31 0 16 % S
% Thr: 8 8 0 8 8 8 8 62 0 0 0 0 31 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 8 0 0 8 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 16 0 8 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _