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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPSR1 All Species: 29.39
Human Site: T74 Identified Species: 53.89
UniProt: Q6W5P4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6W5P4 NP_997055.1 371 42687 T74 N S V V L F S T W R R K K K S
Chimpanzee Pan troglodytes XP_001168820 371 42711 T74 N S V V L F S T W R R K K K S
Rhesus Macaque Macaca mulatta Q56H79 371 42612 T74 N S V V L F S T W R R K R K S
Dog Lupus familis XP_539511 374 42921 T77 N S M V L F S T W R R K R K S
Cat Felis silvestris
Mouse Mus musculus Q8BZP8 371 42420 T74 N S V V L F S T C R R K R K S
Rat Rattus norvegicus P0C0L6 372 42620 T74 N S V V L F S T W R R K R K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519137 132 15251
Chicken Gallus gallus XP_426022 373 42686 T74 N A I V L F S T W R R K R K S
Frog Xenopus laevis P70031 453 51139 V94 T L I I I V L V M N K R L R T
Zebra Danio Brachydanio rerio XP_001341507 388 44497 S74 H T A K H S Q S R M Y Y F M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q868T3 506 55785 F149 S A V L F V M F I N K N R K S
Honey Bee Apis mellifera XP_001122652 353 39441 T62 L T D I I W K T T V S W H A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784373 461 51252 W78 S I V V H S L W R R R K K L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97 88.2 N.A. 89.2 88.9 N.A. 31 73.9 22.5 30.4 N.A. 31.6 35 N.A. 27.5
Protein Similarity: 100 99.4 98.6 93.8 N.A. 94.3 94.6 N.A. 34.5 86.3 40.4 50 N.A. 47.8 54.4 N.A. 45.1
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 93.3 N.A. 0 80 0 0 N.A. 20 6.6 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 0 100 46.6 20 N.A. 53.3 33.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 0 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 54 0 8 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 8 0 0 0 16 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 16 16 16 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 8 0 0 0 16 62 24 62 8 % K
% Leu: 8 8 0 8 54 0 16 0 0 0 0 0 8 8 0 % L
% Met: 0 0 8 0 0 0 8 0 8 8 0 0 0 8 0 % M
% Asn: 54 0 0 0 0 0 0 0 0 16 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 16 62 62 8 47 8 0 % R
% Ser: 16 47 0 0 0 16 54 8 0 0 8 0 0 0 70 % S
% Thr: 8 16 0 0 0 0 0 62 8 0 0 0 0 0 8 % T
% Val: 0 0 54 62 0 16 0 8 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 8 47 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _