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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW12
All Species:
0.91
Human Site:
T305
Identified Species:
6.67
UniProt:
Q6X9E4
Number Species:
3
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6X9E4
NP_996985.2
464
53056
T305
T
L
M
S
Q
S
S
T
G
K
K
T
E
F
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541895
461
52045
T290
I
L
P
M
V
F
L
T
E
C
L
L
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9QZH7
276
30442
C127
E
V
L
S
L
N
G
C
T
K
T
T
D
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507868
403
44980
F254
G
H
M
S
I
T
T
F
D
I
I
T
K
K
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
53.2
N.A.
N.A.
20.4
N.A.
28.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
70
N.A.
N.A.
33.6
N.A.
43.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
N.A.
46.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
25
0
25
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
0
0
0
25
0
0
% D
% Glu:
25
0
0
0
0
0
0
0
25
0
0
0
25
0
0
% E
% Phe:
0
0
0
0
0
25
0
25
0
0
0
0
0
25
0
% F
% Gly:
25
0
0
0
0
0
25
0
25
0
0
0
0
0
0
% G
% His:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
0
0
25
0
0
0
0
25
25
0
0
0
25
% I
% Lys:
0
0
0
0
0
0
0
0
0
50
25
0
50
25
0
% K
% Leu:
0
50
25
0
25
0
25
0
0
0
25
25
0
0
0
% L
% Met:
0
0
50
25
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
25
0
0
0
0
0
0
0
0
0
0
25
0
% P
% Gln:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
75
0
25
25
0
0
0
0
0
0
0
50
% S
% Thr:
25
0
0
0
0
25
25
50
25
0
25
75
0
0
25
% T
% Val:
0
25
0
0
25
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _