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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCL4
All Species:
13.64
Human Site:
S158
Identified Species:
30
UniProt:
Q6XD76
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XD76
NP_982260.2
172
19253
S158
S
D
G
E
S
K
A
S
S
A
P
S
P
S
S
Chimpanzee
Pan troglodytes
Q5IS79
356
38366
P315
M
A
Q
K
N
L
S
P
S
L
P
G
S
I
L
Rhesus Macaque
Macaca mulatta
XP_001101479
172
19014
S158
S
D
G
E
S
K
A
S
S
A
P
S
P
S
S
Dog
Lupus familis
XP_853382
173
19098
S159
S
D
G
E
S
K
A
S
S
A
P
S
P
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJR7
174
20227
T161
E
T
K
K
N
P
R
T
A
S
C
G
S
L
D
Rat
Rattus norvegicus
P19359
233
24953
A202
S
N
D
L
N
S
M
A
G
S
P
V
S
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508823
182
20439
S168
S
D
G
E
S
K
T
S
L
A
S
S
P
Y
S
Chicken
Gallus gallus
P59101
187
20543
P152
G
G
G
G
G
S
P
P
P
R
D
S
E
N
S
Frog
Xenopus laevis
Q06234
199
22356
A168
S
H
D
M
N
S
M
A
G
S
P
V
S
S
Y
Zebra Danio
Brachydanio rerio
Q90259
196
21910
A165
S
N
D
M
N
S
M
A
G
S
P
V
S
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10007
268
30806
N251
F
Q
E
E
S
E
G
N
I
L
I
D
I
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.3
90.1
68.2
N.A.
40.7
26.6
N.A.
54.9
25.6
27.1
27
N.A.
N.A.
N.A.
24.2
N.A.
Protein Similarity:
100
29.7
92.4
74.5
N.A.
51.1
42
N.A.
62.6
33.6
43.2
42.3
N.A.
N.A.
N.A.
36.1
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
0
20
N.A.
73.3
20
20
20
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
33.3
46.6
N.A.
73.3
26.6
40
46.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
28
28
10
37
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
37
28
0
0
0
0
0
0
0
10
10
0
0
10
% D
% Glu:
10
0
10
46
0
10
0
0
0
0
0
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
46
10
10
0
10
0
28
0
0
19
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
0
10
10
0
% I
% Lys:
0
0
10
19
0
37
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
0
10
19
0
0
0
10
10
% L
% Met:
10
0
0
19
0
0
28
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
46
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
10
19
10
0
64
0
37
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% R
% Ser:
64
0
0
0
46
37
10
37
37
37
10
46
46
55
46
% S
% Thr:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
28
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _