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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASCL4 All Species: 10.61
Human Site: S159 Identified Species: 23.33
UniProt: Q6XD76 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6XD76 NP_982260.2 172 19253 S159 D G E S K A S S A P S P S S E
Chimpanzee Pan troglodytes Q5IS79 356 38366 S316 A Q K N L S P S L P G S I L Q
Rhesus Macaque Macaca mulatta XP_001101479 172 19014 S159 D G E S K A S S A P S P S S E
Dog Lupus familis XP_853382 173 19098 S160 D G E S K A S S A P S P C S E
Cat Felis silvestris
Mouse Mus musculus Q9JJR7 174 20227 A162 T K K N P R T A S C G S L D P
Rat Rattus norvegicus P19359 233 24953 G203 N D L N S M A G S P V S S Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508823 182 20439 L169 D G E S K T S L A S S P Y S E
Chicken Gallus gallus P59101 187 20543 P153 G G G G S P P P R D S E N S Q
Frog Xenopus laevis Q06234 199 22356 G169 H D M N S M A G S P V S S Y S
Zebra Danio Brachydanio rerio Q90259 196 21910 G166 N D M N S M A G S P V S S Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10007 268 30806 I252 Q E E S E G N I L I D I S T F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.3 90.1 68.2 N.A. 40.7 26.6 N.A. 54.9 25.6 27.1 27 N.A. N.A. N.A. 24.2 N.A.
Protein Similarity: 100 29.7 92.4 74.5 N.A. 51.1 42 N.A. 62.6 33.6 43.2 42.3 N.A. N.A. N.A. 36.1 N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 0 13.3 N.A. 73.3 20 13.3 13.3 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 40 100 93.3 N.A. 33.3 40 N.A. 73.3 33.3 33.3 40 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 28 28 10 37 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % C
% Asp: 37 28 0 0 0 0 0 0 0 10 10 0 0 10 0 % D
% Glu: 0 10 46 0 10 0 0 0 0 0 0 10 0 0 37 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 46 10 10 0 10 0 28 0 0 19 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 10 0 10 10 0 0 % I
% Lys: 0 10 19 0 37 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 0 0 10 19 0 0 0 10 10 0 % L
% Met: 0 0 19 0 0 28 0 0 0 0 0 0 0 0 0 % M
% Asn: 19 0 0 46 0 0 10 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 10 19 10 0 64 0 37 0 0 10 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 19 % Q
% Arg: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 46 37 10 37 37 37 10 46 46 55 46 28 % S
% Thr: 10 0 0 0 0 10 10 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 28 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _