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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAPRT1
All Species:
17.88
Human Site:
S222
Identified Species:
32.78
UniProt:
Q6XQN6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XQN6
NP_660202.3
538
57578
S222
F
V
T
S
F
S
G
S
E
V
P
P
D
P
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097478
470
50208
S222
F
V
T
S
F
S
G
S
E
V
P
P
D
P
M
Dog
Lupus familis
XP_851754
503
53958
T187
F
V
T
S
F
S
G
T
E
V
P
P
D
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC86
538
58247
S222
F
V
T
S
F
S
G
S
E
V
P
P
D
P
M
Rat
Rattus norvegicus
Q6XQN1
538
58546
S222
F
I
T
S
F
L
G
S
E
V
P
P
D
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996864
386
42097
A152
L
P
N
F
C
A
V
A
L
A
L
H
Q
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P3H4
546
59690
L221
Y
I
T
S
F
S
S
L
E
E
V
W
P
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQX4
555
62147
I234
Y
I
T
S
F
S
S
I
G
E
L
K
T
R
L
Honey Bee
Apis mellifera
XP_623279
549
62152
L228
Y
I
T
S
F
I
T
L
D
D
L
R
E
K
T
Nematode Worm
Caenorhab. elegans
Q95XX1
563
63427
P237
F
I
C
S
F
S
S
P
A
E
L
K
V
R
L
Sea Urchin
Strong. purpuratus
XP_787773
571
63663
L253
F
V
M
S
Y
G
G
L
D
E
V
K
N
R
V
Poplar Tree
Populus trichocarpa
XP_002310133
559
62263
P233
F
V
S
S
Y
M
S
P
D
E
I
I
D
K
S
Maize
Zea mays
NP_001142107
569
63510
L243
F
V
S
S
F
M
G
L
D
E
I
T
D
K
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.5
81.5
N.A.
83.8
81
N.A.
N.A.
41.6
N.A.
54.9
N.A.
45
45.3
41.9
45.1
Protein Similarity:
100
N.A.
85.5
86.6
N.A.
89.9
88.8
N.A.
N.A.
52.9
N.A.
69.2
N.A.
63.4
63.5
61.6
63.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
86.6
N.A.
N.A.
0
N.A.
33.3
N.A.
26.6
20
26.6
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
13.3
N.A.
46.6
N.A.
46.6
46.6
40
53.3
Percent
Protein Identity:
44.7
45.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
61.1
60.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
53.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
8
8
0
0
0
0
0
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
31
8
0
0
54
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
47
47
0
0
8
0
0
% E
% Phe:
70
0
0
8
77
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
54
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
39
0
0
0
8
0
8
0
0
16
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
24
0
24
0
% K
% Leu:
8
0
0
0
0
8
0
31
8
0
31
0
0
8
16
% L
% Met:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
39
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
16
0
0
39
39
8
39
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
24
0
% R
% Ser:
0
0
16
93
0
54
31
31
0
0
0
0
0
0
8
% S
% Thr:
0
0
62
0
0
0
8
8
0
0
0
8
8
0
24
% T
% Val:
0
54
0
0
0
0
8
0
0
39
16
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
24
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _