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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAPRT1
All Species:
22.73
Human Site:
S432
Identified Species:
41.67
UniProt:
Q6XQN6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XQN6
NP_660202.3
538
57578
S432
R
L
L
G
S
D
G
S
P
L
M
D
M
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097478
470
50208
S381
N
V
I
G
I
G
T
S
V
V
T
C
P
Q
Q
Dog
Lupus familis
XP_851754
503
53958
S397
R
L
L
G
P
E
G
S
L
L
L
D
V
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC86
538
58247
S432
R
F
L
G
P
D
G
S
L
L
L
D
L
L
Q
Rat
Rattus norvegicus
Q6XQN1
538
58546
S432
R
F
L
V
S
E
G
S
L
L
L
D
L
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996864
386
42097
R308
A
V
H
I
L
G
R
R
G
E
A
T
K
I
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P3H4
546
59690
H430
R
L
L
D
A
D
G
H
P
Q
M
D
V
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQX4
555
62147
H443
R
L
Y
S
A
D
G
H
A
L
I
D
L
L
Q
Honey Bee
Apis mellifera
XP_623279
549
62152
C437
R
L
Y
G
A
D
G
C
A
L
I
D
L
L
Q
Nematode Worm
Caenorhab. elegans
Q95XX1
563
63427
Y449
R
I
F
G
K
N
G
Y
A
I
L
D
L
M
M
Sea Urchin
Strong. purpuratus
XP_787773
571
63663
H459
R
L
F
S
S
E
G
H
A
L
I
D
L
M
Q
Poplar Tree
Populus trichocarpa
XP_002310133
559
62263
Y445
R
L
Y
G
R
E
G
Y
P
L
V
D
I
M
T
Maize
Zea mays
NP_001142107
569
63510
Y455
R
L
Y
G
K
E
G
Y
P
L
V
D
I
M
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.5
81.5
N.A.
83.8
81
N.A.
N.A.
41.6
N.A.
54.9
N.A.
45
45.3
41.9
45.1
Protein Similarity:
100
N.A.
85.5
86.6
N.A.
89.9
88.8
N.A.
N.A.
52.9
N.A.
69.2
N.A.
63.4
63.5
61.6
63.9
P-Site Identity:
100
N.A.
20
66.6
N.A.
66.6
60
N.A.
N.A.
0
N.A.
60
N.A.
53.3
60
26.6
46.6
P-Site Similarity:
100
N.A.
40
86.6
N.A.
80
80
N.A.
N.A.
20
N.A.
73.3
N.A.
73.3
80
66.6
73.3
Percent
Protein Identity:
44.7
45.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
61.1
60.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
46.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
73.3
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
24
0
0
0
31
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% C
% Asp:
0
0
0
8
0
39
0
0
0
0
0
85
0
0
0
% D
% Glu:
0
0
0
0
0
39
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
16
16
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
62
0
16
85
0
8
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
24
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
8
0
0
0
0
8
24
0
16
8
0
% I
% Lys:
0
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
62
39
0
8
0
0
0
24
70
31
0
47
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
8
31
8
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
31
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
62
% Q
% Arg:
85
0
0
0
8
0
8
8
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
16
24
0
0
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
16
% T
% Val:
0
16
0
8
0
0
0
0
8
8
16
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
31
0
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _