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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAPRT1
All Species:
16.67
Human Site:
S502
Identified Species:
30.56
UniProt:
Q6XQN6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XQN6
NP_660202.3
538
57578
S502
A
L
A
Q
L
S
L
S
R
L
S
P
E
H
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097478
470
50208
S434
A
L
V
Q
L
S
L
S
Q
L
S
P
E
H
R
Dog
Lupus familis
XP_851754
503
53958
S467
A
F
A
Q
L
S
L
S
R
L
S
P
E
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC86
538
58247
S502
R
F
A
Q
Q
S
L
S
L
L
R
P
A
H
K
Rat
Rattus norvegicus
Q6XQN1
538
58546
S502
A
F
A
Q
Q
S
L
S
R
L
R
P
A
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996864
386
42097
N351
S
H
A
Q
A
S
L
N
L
L
S
P
V
H
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P3H4
546
59690
Q502
E
R
A
Q
I
S
L
Q
M
L
N
P
Y
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQX4
555
62147
K514
E
K
V
Q
I
S
L
K
T
L
R
N
D
H
K
Honey Bee
Apis mellifera
XP_623279
549
62152
R508
N
K
V
Q
E
S
L
R
T
L
R
N
D
H
K
Nematode Worm
Caenorhab. elegans
Q95XX1
563
63427
S522
H
V
N
E
S
I
R
S
T
L
R
Q
D
H
R
Sea Urchin
Strong. purpuratus
XP_787773
571
63663
D530
Q
L
V
Q
D
S
L
D
S
L
R
H
D
H
K
Poplar Tree
Populus trichocarpa
XP_002310133
559
62263
E518
D
S
C
I
K
Q
L
E
R
M
R
P
D
H
M
Maize
Zea mays
NP_001142107
569
63510
D528
T
R
C
I
H
H
L
D
R
M
R
P
D
H
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.5
81.5
N.A.
83.8
81
N.A.
N.A.
41.6
N.A.
54.9
N.A.
45
45.3
41.9
45.1
Protein Similarity:
100
N.A.
85.5
86.6
N.A.
89.9
88.8
N.A.
N.A.
52.9
N.A.
69.2
N.A.
63.4
63.5
61.6
63.9
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
53.3
66.6
N.A.
N.A.
60
N.A.
46.6
N.A.
33.3
33.3
26.6
40
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
60
73.3
N.A.
N.A.
73.3
N.A.
66.6
N.A.
53.3
46.6
46.6
53.3
Percent
Protein Identity:
44.7
45.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
61.1
60.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
47
0
8
0
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
16
0
0
0
0
47
0
0
% D
% Glu:
16
0
0
8
8
0
0
8
0
0
0
0
24
0
0
% E
% Phe:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
8
0
0
8
8
0
0
0
0
0
8
0
100
0
% H
% Ile:
0
0
0
16
16
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
16
0
0
8
0
0
8
0
0
0
0
0
0
54
% K
% Leu:
0
24
0
0
24
0
93
0
16
85
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
16
0
0
0
0
16
% M
% Asn:
8
0
8
0
0
0
0
8
0
0
8
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% P
% Gln:
8
0
0
77
16
8
0
8
8
0
0
8
0
0
0
% Q
% Arg:
8
16
0
0
0
0
8
8
39
0
62
0
0
0
31
% R
% Ser:
8
8
0
0
8
77
0
47
8
0
31
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% T
% Val:
0
8
31
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _