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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAPRT1
All Species:
33.94
Human Site:
T416
Identified Species:
62.22
UniProt:
Q6XQN6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XQN6
NP_660202.3
538
57578
T416
T
E
D
P
E
K
Q
T
L
P
G
S
K
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097478
470
50208
R365
I
D
E
E
A
L
A
R
L
A
Q
E
G
S
E
Dog
Lupus familis
XP_851754
503
53958
T381
T
E
D
P
E
K
Q
T
L
P
G
S
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC86
538
58247
T416
T
E
D
P
E
K
Q
T
L
P
G
S
K
A
A
Rat
Rattus norvegicus
Q6XQN1
538
58546
T416
T
E
E
S
Q
K
E
T
L
P
G
S
K
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996864
386
42097
P292
L
M
A
L
E
N
E
P
S
P
S
V
G
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P3H4
546
59690
T414
S
E
D
P
E
K
S
T
L
P
G
R
K
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQX4
555
62147
T427
S
Q
D
V
E
K
V
T
M
P
G
N
K
N
A
Honey Bee
Apis mellifera
XP_623279
549
62152
S421
S
H
D
V
S
K
I
S
I
P
G
K
K
V
A
Nematode Worm
Caenorhab. elegans
Q95XX1
563
63427
T433
S
Q
D
V
T
K
I
T
I
P
G
K
K
K
C
Sea Urchin
Strong. purpuratus
XP_787773
571
63663
T443
S
Q
D
V
S
K
V
T
I
P
G
R
K
V
V
Poplar Tree
Populus trichocarpa
XP_002310133
559
62263
S429
S
E
D
V
S
K
V
S
I
P
C
K
K
R
S
Maize
Zea mays
NP_001142107
569
63510
S439
S
E
D
V
M
K
V
S
I
P
C
K
K
K
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.5
81.5
N.A.
83.8
81
N.A.
N.A.
41.6
N.A.
54.9
N.A.
45
45.3
41.9
45.1
Protein Similarity:
100
N.A.
85.5
86.6
N.A.
89.9
88.8
N.A.
N.A.
52.9
N.A.
69.2
N.A.
63.4
63.5
61.6
63.9
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
73.3
N.A.
N.A.
13.3
N.A.
73.3
N.A.
53.3
40
40
40
P-Site Similarity:
100
N.A.
26.6
100
N.A.
100
93.3
N.A.
N.A.
20
N.A.
80
N.A.
80
60
60
60
Percent
Protein Identity:
44.7
45.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
61.1
60.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
33.3
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
53.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
0
0
8
0
0
0
39
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
16
% C
% Asp:
0
8
77
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
54
16
8
47
0
16
0
0
0
0
8
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
70
0
16
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
16
0
39
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
85
0
0
0
0
0
31
85
16
0
% K
% Leu:
8
0
0
8
0
8
0
0
47
0
0
0
0
0
0
% L
% Met:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
31
0
0
0
8
0
93
0
0
0
0
0
% P
% Gln:
0
24
0
0
8
0
24
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
16
0
8
0
% R
% Ser:
54
0
0
8
24
0
8
24
8
0
8
31
0
8
8
% S
% Thr:
31
0
0
0
8
0
0
62
0
0
0
0
0
0
0
% T
% Val:
0
0
0
47
0
0
31
0
0
0
0
8
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _