Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAPRT1 All Species: 36.06
Human Site: Y29 Identified Species: 66.11
UniProt: Q6XQN6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6XQN6 NP_660202.3 538 57578 Y29 Q A T M A L G Y W R A G R A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097478 470 50208 Y29 Q A T M A L G Y W R A G R A R
Dog Lupus familis XP_851754 503 53958 Y29 Q A T M A L G Y W R A G R A R
Cat Felis silvestris
Mouse Mus musculus Q8CC86 538 58247 Y29 Q A T M A L G Y W R A G R A C
Rat Rattus norvegicus Q6XQN1 538 58546 Y29 Q A T M G L G Y W R A G R A C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_996864 386 42097 E13 A F L L A A D E A D G V G S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6P3H4 546 59690 Y28 L Y Q M A Y A Y W R A G R H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQX4 555 62147 Y41 Q I T M A Y A Y W K S D K T D
Honey Bee Apis mellifera XP_623279 549 62152 Y35 Q I T M A Y A Y W K S E K M N
Nematode Worm Caenorhab. elegans Q95XX1 563 63427 Y44 Q I T M C Y A Y W K T G T H N
Sea Urchin Strong. purpuratus XP_787773 571 63663 Y60 Q V T M A Y A Y W K S E R T N
Poplar Tree Populus trichocarpa XP_002310133 559 62263 Y40 Q F T M A Y A Y W K A N K H Q
Maize Zea mays NP_001142107 569 63510 Y39 Q F T M A Y A Y W K A G K H L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 84.5 81.5 N.A. 83.8 81 N.A. N.A. 41.6 N.A. 54.9 N.A. 45 45.3 41.9 45.1
Protein Similarity: 100 N.A. 85.5 86.6 N.A. 89.9 88.8 N.A. N.A. 52.9 N.A. 69.2 N.A. 63.4 63.5 61.6 63.9
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 86.6 N.A. N.A. 6.6 N.A. 53.3 N.A. 40 40 40 46.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 86.6 N.A. N.A. 20 N.A. 53.3 N.A. 60 60 46.6 60
Percent
Protein Identity: 44.7 45.5 N.A. N.A. N.A. N.A.
Protein Similarity: 61.1 60.8 N.A. N.A. N.A. N.A.
P-Site Identity: 46.6 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 66.6 66.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 39 0 0 85 8 54 0 8 0 62 0 0 39 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 16 % C
% Asp: 0 0 0 0 0 0 8 0 0 8 0 8 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 16 0 0 0 % E
% Phe: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 39 0 0 0 8 62 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 % H
% Ile: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 47 0 0 31 0 0 % K
% Leu: 8 0 8 8 0 39 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 93 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 31 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 85 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 47 0 0 54 0 24 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 24 0 0 8 0 % S
% Thr: 0 0 85 0 0 0 0 0 0 0 8 0 8 16 8 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 54 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _