KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAPRT1
All Species:
38.48
Human Site:
Y517
Identified Species:
70.56
UniProt:
Q6XQN6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XQN6
NP_660202.3
538
57578
Y517
R
L
R
S
P
A
Q
Y
Q
V
V
L
S
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097478
470
50208
Y449
R
L
Q
S
P
A
Q
Y
Q
V
V
L
S
E
R
Dog
Lupus familis
XP_851754
503
53958
Y482
R
L
E
W
P
A
L
Y
Q
V
A
L
S
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC86
538
58247
Y517
Q
L
Q
S
P
A
V
Y
P
V
A
L
S
E
K
Rat
Rattus norvegicus
Q6XQN1
538
58546
Y517
Q
L
Q
N
P
A
V
Y
Q
V
A
L
S
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996864
386
42097
Y366
Q
L
R
D
P
Q
P
Y
P
V
A
V
T
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P3H4
546
59690
Y517
R
L
Q
E
P
H
N
Y
T
V
A
L
S
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQX4
555
62147
Y529
R
T
L
N
P
T
P
Y
K
V
A
V
S
D
N
Honey Bee
Apis mellifera
XP_623279
549
62152
Y523
R
N
L
N
P
T
P
Y
K
V
A
V
S
D
D
Nematode Worm
Caenorhab. elegans
Q95XX1
563
63427
Y537
R
Y
L
N
P
T
P
Y
K
V
S
V
S
E
R
Sea Urchin
Strong. purpuratus
XP_787773
571
63663
Y545
R
A
L
N
P
T
P
Y
K
V
S
V
S
D
R
Poplar Tree
Populus trichocarpa
XP_002310133
559
62263
Y533
R
R
L
N
P
T
P
Y
K
V
S
V
S
A
K
Maize
Zea mays
NP_001142107
569
63510
Y543
R
R
L
N
P
T
P
Y
K
V
S
V
S
A
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.5
81.5
N.A.
83.8
81
N.A.
N.A.
41.6
N.A.
54.9
N.A.
45
45.3
41.9
45.1
Protein Similarity:
100
N.A.
85.5
86.6
N.A.
89.9
88.8
N.A.
N.A.
52.9
N.A.
69.2
N.A.
63.4
63.5
61.6
63.9
P-Site Identity:
100
N.A.
93.3
60
N.A.
60
60
N.A.
N.A.
40
N.A.
60
N.A.
33.3
33.3
46.6
40
P-Site Similarity:
100
N.A.
100
73.3
N.A.
80
86.6
N.A.
N.A.
66.6
N.A.
66.6
N.A.
60
60
66.6
66.6
Percent
Protein Identity:
44.7
45.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
61.1
60.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
33.3
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
39
0
0
0
0
54
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
31
8
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
0
0
0
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
47
% K
% Leu:
0
54
47
0
0
0
8
0
0
0
0
47
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
54
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
100
0
54
0
16
0
0
0
0
0
0
% P
% Gln:
24
0
31
0
0
8
16
0
31
0
0
0
0
0
0
% Q
% Arg:
77
16
16
0
0
0
0
0
0
0
0
0
0
0
39
% R
% Ser:
0
0
0
24
0
0
0
0
0
0
31
0
93
0
0
% S
% Thr:
0
8
0
0
0
47
0
0
8
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
16
0
0
100
16
54
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _