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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLB
All Species:
23.33
Human Site:
S181
Identified Species:
42.78
UniProt:
Q6Y1H2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Y1H2
NP_940684.1
254
28368
S181
V
L
Y
P
M
G
V
S
G
E
L
L
T
I
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113078
254
28296
S181
V
L
Y
P
M
G
V
S
G
E
L
L
T
I
Y
Dog
Lupus familis
XP_850968
216
25210
G144
L
Y
P
M
G
V
S
G
E
L
L
T
I
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3B1
254
28384
T181
V
L
Y
P
M
G
V
T
G
E
L
L
T
I
Y
Rat
Rattus norvegicus
XP_213610
254
28333
T181
V
L
Y
P
M
G
V
T
G
E
L
L
T
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519816
207
23678
T135
A
L
Y
P
M
G
V
T
G
E
L
L
T
I
Y
Chicken
Gallus gallus
Q5ZM57
362
42817
G290
I
P
L
Y
P
L
G
G
L
A
E
A
V
C
L
Frog
Xenopus laevis
Q6GNB5
218
25718
L146
V
A
Y
P
L
S
V
L
A
E
A
Y
T
I
Y
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
V287
M
P
L
Y
P
L
G
V
L
A
E
A
V
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504740
218
24628
V146
Y
V
L
Y
P
M
G
V
S
G
E
L
L
T
L
Sea Urchin
Strong. purpuratus
XP_796799
235
26468
T162
V
L
Y
P
I
G
V
T
G
E
L
W
T
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZB2
221
25308
T149
S
F
L
L
L
Y
P
T
G
I
T
S
E
V
G
Baker's Yeast
Sacchar. cerevisiae
P40857
217
24492
F145
I
L
L
R
Y
N
L
F
W
I
L
Y
P
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
81
N.A.
94.8
93.6
N.A.
49.6
21.2
24
22.2
N.A.
N.A.
N.A.
40.9
56.6
Protein Similarity:
100
N.A.
99.6
83.4
N.A.
98
97.6
N.A.
58.2
38.9
42.9
40.6
N.A.
N.A.
N.A.
56.2
71.2
P-Site Identity:
100
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
86.6
0
53.3
0
N.A.
N.A.
N.A.
6.6
80
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
6.6
60
6.6
N.A.
N.A.
N.A.
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
8
16
8
16
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
54
24
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
47
24
16
54
8
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
8
0
0
0
0
16
0
0
8
54
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
54
39
8
16
16
8
8
16
8
62
47
8
0
16
% L
% Met:
8
0
0
8
39
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
8
54
24
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
8
16
8
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
39
0
0
8
8
54
16
0
% T
% Val:
47
8
0
0
0
8
54
16
0
0
0
0
16
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
8
8
54
24
8
8
0
0
0
0
0
16
0
8
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _