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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLB
All Species:
24.24
Human Site:
S76
Identified Species:
44.44
UniProt:
Q6Y1H2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Y1H2
NP_940684.1
254
28368
S76
S
Y
H
S
L
Y
Y
S
I
E
K
P
L
K
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113078
254
28296
S76
S
Y
H
S
L
Y
Y
S
I
E
K
P
L
K
F
Dog
Lupus familis
XP_850968
216
25210
E40
H
S
L
Y
Y
S
I
E
K
P
L
K
F
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3B1
254
28384
S76
S
Y
H
S
L
Y
Y
S
I
E
R
P
L
K
F
Rat
Rattus norvegicus
XP_213610
254
28333
S76
S
Y
H
S
L
Y
Y
S
I
E
K
P
L
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519816
207
23678
E31
A
R
P
S
R
V
M
E
G
H
G
A
L
T
G
Chicken
Gallus gallus
Q5ZM57
362
42817
T186
S
F
Y
D
T
F
H
T
I
A
D
M
M
Y
F
Frog
Xenopus laevis
Q6GNB5
218
25718
S41
A
F
A
D
T
F
Y
S
I
G
L
V
M
Q
G
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
T183
S
F
Y
D
T
F
H
T
I
A
D
V
M
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504740
218
24628
S41
T
W
P
Q
L
Y
E
S
V
E
F
E
L
K
I
Sea Urchin
Strong. purpuratus
XP_796799
235
26468
I58
N
V
G
L
Y
D
A
I
E
L
P
L
K
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZB2
221
25308
D45
T
G
Y
E
N
V
Y
D
A
I
E
K
P
L
Q
Baker's Yeast
Sacchar. cerevisiae
P40857
217
24492
A41
Y
P
K
V
G
Q
P
A
F
F
Y
Q
T
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
81
N.A.
94.8
93.6
N.A.
49.6
21.2
24
22.2
N.A.
N.A.
N.A.
40.9
56.6
Protein Similarity:
100
N.A.
99.6
83.4
N.A.
98
97.6
N.A.
58.2
38.9
42.9
40.6
N.A.
N.A.
N.A.
56.2
71.2
P-Site Identity:
100
N.A.
100
0
N.A.
93.3
100
N.A.
13.3
20
20
20
N.A.
N.A.
N.A.
40
6.6
P-Site Similarity:
100
N.A.
100
0
N.A.
100
100
N.A.
20
60
53.3
60
N.A.
N.A.
N.A.
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
8
8
8
16
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
8
0
8
0
0
16
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
8
16
8
39
8
8
0
0
0
% E
% Phe:
0
24
0
0
0
24
0
0
8
8
8
0
8
8
54
% F
% Gly:
0
8
8
0
8
0
0
0
8
8
8
0
0
0
16
% G
% His:
8
0
31
0
0
0
16
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
54
8
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
8
0
24
16
8
47
0
% K
% Leu:
0
0
8
8
39
0
0
0
0
8
16
8
47
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
24
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
16
0
0
0
8
0
0
8
8
31
8
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
0
8
0
8
16
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
47
8
0
39
0
8
0
47
0
0
0
0
0
0
0
% S
% Thr:
16
0
0
0
24
0
0
16
0
0
0
0
8
8
0
% T
% Val:
0
8
0
8
0
16
0
0
8
0
0
16
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
31
24
8
16
39
47
0
0
0
8
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _