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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLB
All Species:
23.64
Human Site:
Y162
Identified Species:
43.33
UniProt:
Q6Y1H2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Y1H2
NP_940684.1
254
28368
Y162
S
L
L
N
H
L
P
Y
L
I
K
W
A
R
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113078
254
28296
Y162
S
L
L
N
H
L
P
Y
L
I
K
W
A
R
Y
Dog
Lupus familis
XP_850968
216
25210
L125
L
L
N
H
L
P
Y
L
I
K
W
A
R
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3B1
254
28384
Y162
S
L
L
N
H
L
P
Y
I
I
K
W
A
R
Y
Rat
Rattus norvegicus
XP_213610
254
28333
Y162
S
L
L
N
H
L
P
Y
I
I
K
W
A
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519816
207
23678
Y116
S
L
L
D
H
L
P
Y
L
I
K
W
T
R
Y
Chicken
Gallus gallus
Q5ZM57
362
42817
W271
L
S
C
M
G
I
E
W
K
P
L
T
W
L
R
Frog
Xenopus laevis
Q6GNB5
218
25718
S127
A
A
V
D
T
D
Y
S
A
L
T
W
L
R
H
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
W268
L
A
C
I
D
T
E
W
K
L
L
T
W
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504740
218
24628
P127
S
V
L
K
Q
P
I
P
Y
F
L
L
Y
L
R
Sea Urchin
Strong. purpuratus
XP_796799
235
26468
Y143
A
L
L
N
R
L
P
Y
V
L
M
W
L
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZB2
221
25308
F130
G
F
K
E
A
L
G
F
A
P
S
W
H
L
W
Baker's Yeast
Sacchar. cerevisiae
P40857
217
24492
M126
R
Y
L
Y
Y
F
F
M
L
V
F
K
N
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
81
N.A.
94.8
93.6
N.A.
49.6
21.2
24
22.2
N.A.
N.A.
N.A.
40.9
56.6
Protein Similarity:
100
N.A.
99.6
83.4
N.A.
98
97.6
N.A.
58.2
38.9
42.9
40.6
N.A.
N.A.
N.A.
56.2
71.2
P-Site Identity:
100
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
86.6
0
13.3
0
N.A.
N.A.
N.A.
13.3
60
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
93.3
13.3
46.6
13.3
N.A.
N.A.
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
0
0
8
0
0
0
16
0
0
8
31
0
8
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
8
8
8
0
8
8
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
39
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
8
0
8
8
0
24
39
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
0
0
16
8
39
8
0
0
0
% K
% Leu:
24
54
62
0
8
54
0
8
31
24
24
8
16
31
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
39
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
16
47
8
0
16
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
0
0
8
54
24
% R
% Ser:
47
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
8
16
8
0
8
% T
% Val:
0
8
8
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
16
0
0
8
62
16
0
8
% W
% Tyr:
0
8
0
8
8
0
16
47
8
0
0
0
8
8
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _