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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLB
All Species:
22.42
Human Site:
Y208
Identified Species:
41.11
UniProt:
Q6Y1H2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Y1H2
NP_940684.1
254
28368
Y208
S
I
S
L
P
N
K
Y
N
F
S
F
D
Y
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113078
254
28296
Y208
S
I
S
L
P
N
K
Y
N
F
S
F
D
Y
H
Dog
Lupus familis
XP_850968
216
25210
N171
I
S
L
P
N
K
Y
N
F
S
F
D
Y
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3B1
254
28384
Y208
S
I
S
L
P
N
K
Y
N
F
S
F
D
Y
H
Rat
Rattus norvegicus
XP_213610
254
28333
Y208
S
I
S
L
P
N
K
Y
N
F
S
F
D
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519816
207
23678
Y162
S
V
S
L
P
N
K
Y
N
F
S
F
D
Y
H
Chicken
Gallus gallus
Q5ZM57
362
42817
P317
F
S
L
G
L
P
N
P
L
N
V
T
I
Q
F
Frog
Xenopus laevis
Q6GNB5
218
25718
V173
S
F
K
M
A
L
P
V
S
L
S
F
H
F
P
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
A314
L
S
I
P
L
P
K
A
T
G
L
S
L
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504740
218
24628
R173
L
T
L
E
M
P
N
R
L
N
M
G
I
S
F
Sea Urchin
Strong. purpuratus
XP_796799
235
26468
Y189
S
L
E
L
P
N
D
Y
N
I
S
F
D
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZB2
221
25308
P176
E
M
Y
S
V
R
M
P
N
I
L
N
F
S
F
Baker's Yeast
Sacchar. cerevisiae
P40857
217
24492
S172
N
A
A
E
S
Q
Y
S
L
L
Y
K
R
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
81
N.A.
94.8
93.6
N.A.
49.6
21.2
24
22.2
N.A.
N.A.
N.A.
40.9
56.6
Protein Similarity:
100
N.A.
99.6
83.4
N.A.
98
97.6
N.A.
58.2
38.9
42.9
40.6
N.A.
N.A.
N.A.
56.2
71.2
P-Site Identity:
100
N.A.
93.3
6.6
N.A.
93.3
93.3
N.A.
86.6
0
20
6.6
N.A.
N.A.
N.A.
0
73.3
P-Site Similarity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
100
6.6
40
13.3
N.A.
N.A.
N.A.
6.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
8
47
0
0
% D
% Glu:
8
0
8
16
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
8
39
8
54
8
8
31
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
31
% H
% Ile:
8
31
8
0
0
0
0
0
0
16
0
0
16
8
0
% I
% Lys:
0
0
8
0
0
8
47
0
0
0
0
8
0
0
0
% K
% Leu:
16
8
24
47
16
8
0
0
24
16
16
0
8
0
8
% L
% Met:
0
8
0
8
8
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
8
47
16
8
54
16
0
8
0
0
0
% N
% Pro:
0
0
0
16
47
24
8
16
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% R
% Ser:
54
24
39
8
8
0
0
8
8
8
54
8
0
24
0
% S
% Thr:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% T
% Val:
0
8
0
0
8
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
16
47
0
0
8
0
8
54
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _