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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLB
All Species:
13.64
Human Site:
Y70
Identified Species:
25
UniProt:
Q6Y1H2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Y1H2
NP_940684.1
254
28368
Y70
A
Y
L
A
K
G
S
Y
H
S
L
Y
Y
S
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113078
254
28296
Y70
A
Y
L
A
K
G
S
Y
H
S
L
Y
Y
S
I
Dog
Lupus familis
XP_850968
216
25210
S34
L
A
K
G
S
Y
H
S
L
Y
Y
S
I
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3B1
254
28384
Y70
A
Y
L
A
K
G
S
Y
H
S
L
Y
Y
S
I
Rat
Rattus norvegicus
XP_213610
254
28333
Y70
A
Y
L
A
K
G
S
Y
H
S
L
Y
Y
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519816
207
23678
R25
L
G
Q
D
G
R
A
R
P
S
R
V
M
E
G
Chicken
Gallus gallus
Q5ZM57
362
42817
F180
F
I
L
G
K
D
S
F
Y
D
T
F
H
T
I
Frog
Xenopus laevis
Q6GNB5
218
25718
F35
L
F
F
G
Q
D
A
F
A
D
T
F
Y
S
I
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
F177
F
I
L
G
Q
D
S
F
Y
D
T
F
H
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504740
218
24628
W35
G
L
A
N
G
L
T
W
P
Q
L
Y
E
S
V
Sea Urchin
Strong. purpuratus
XP_796799
235
26468
V52
Y
L
Q
E
G
T
N
V
G
L
Y
D
A
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZB2
221
25308
G39
I
T
T
L
K
E
T
G
Y
E
N
V
Y
D
A
Baker's Yeast
Sacchar. cerevisiae
P40857
217
24492
P35
Y
L
V
I
S
L
Y
P
K
V
G
Q
P
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
81
N.A.
94.8
93.6
N.A.
49.6
21.2
24
22.2
N.A.
N.A.
N.A.
40.9
56.6
Protein Similarity:
100
N.A.
99.6
83.4
N.A.
98
97.6
N.A.
58.2
38.9
42.9
40.6
N.A.
N.A.
N.A.
56.2
71.2
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
6.6
26.6
20
20
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
N.A.
100
0
N.A.
100
100
N.A.
13.3
60
53.3
60
N.A.
N.A.
N.A.
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
8
8
31
0
0
16
0
8
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
24
0
0
0
24
0
8
0
8
0
% D
% Glu:
0
0
0
8
0
8
0
0
0
8
0
0
8
16
8
% E
% Phe:
16
8
8
0
0
0
0
24
0
0
0
24
0
0
8
% F
% Gly:
8
8
0
31
24
31
0
8
8
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
31
0
0
0
16
0
0
% H
% Ile:
8
16
0
8
0
0
0
0
0
0
0
0
8
8
54
% I
% Lys:
0
0
8
0
47
0
0
0
8
0
0
0
0
0
8
% K
% Leu:
24
24
47
8
0
16
0
0
8
8
39
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
16
0
0
0
8
0
0
% P
% Gln:
0
0
16
0
16
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
16
0
47
8
0
39
0
8
0
47
0
% S
% Thr:
0
8
8
0
0
8
16
0
0
0
24
0
0
16
0
% T
% Val:
0
0
8
0
0
0
0
8
0
8
0
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
16
31
0
0
0
8
8
31
24
8
16
39
47
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _