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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GIGYF2
All Species:
16.97
Human Site:
S442
Identified Species:
37.33
UniProt:
Q6Y7W6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Y7W6
NP_001096616.1
1299
150070
S442
Q
P
L
S
Q
I
P
S
D
T
A
S
P
L
L
Chimpanzee
Pan troglodytes
XP_001147956
1301
150322
S442
Q
P
L
S
Q
I
P
S
D
T
A
S
P
L
L
Rhesus Macaque
Macaca mulatta
XP_001114387
1298
149954
S442
Q
P
L
S
Q
I
A
S
D
T
A
S
P
L
L
Dog
Lupus familis
XP_861702
1296
149765
S442
Q
P
L
S
Q
I
P
S
D
T
A
S
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6Y7W8
1291
149174
P443
Q
P
S
T
P
L
P
P
D
T
A
S
P
L
L
Rat
Rattus norvegicus
NP_001100603
1042
115996
G395
K
E
L
P
P
A
E
G
D
E
M
R
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520911
674
76044
S122
A
P
R
G
R
S
S
S
R
G
R
G
R
G
R
Chicken
Gallus gallus
P53352
877
100922
I325
E
S
T
I
R
K
S
I
A
R
T
V
I
K
R
Frog
Xenopus laevis
Q5U236
1239
141618
P402
Q
R
S
P
A
R
Q
P
D
P
H
I
V
P
A
Zebra Danio
Brachydanio rerio
Q4KME6
1335
153036
S461
D
L
P
V
P
A
P
S
V
L
P
V
K
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KQM6
1579
174343
T523
I
Q
I
T
P
T
I
T
D
V
A
P
P
S
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
97.4
N.A.
94.3
46.1
N.A.
46.9
20.5
60.9
61.2
N.A.
20.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.3
98.2
N.A.
95.6
58.7
N.A.
49.4
35.1
73.5
72.5
N.A.
38.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
66.6
20
N.A.
13.3
0
13.3
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
80
26.6
N.A.
20
13.3
13.3
20
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
19
10
0
10
0
55
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
0
10
0
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
10
0
10
10
0
37
10
10
0
0
0
10
10
0
0
% I
% Lys:
10
0
0
0
0
10
0
0
0
0
0
0
10
10
0
% K
% Leu:
0
10
46
0
0
10
0
0
0
10
0
0
0
55
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
55
10
19
37
0
46
19
0
10
10
10
55
10
10
% P
% Gln:
55
10
0
0
37
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
19
10
0
0
10
10
10
10
10
0
19
% R
% Ser:
0
10
19
37
0
10
19
55
0
0
0
46
0
19
0
% S
% Thr:
0
0
10
19
0
10
0
10
0
46
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
10
0
19
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _