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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD109
All Species:
18.18
Human Site:
Y938
Identified Species:
36.36
UniProt:
Q6YHK3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YHK3
NP_001153059.1
1445
161689
Y938
P
N
I
Y
I
L
D
Y
L
T
K
K
K
Q
L
Chimpanzee
Pan troglodytes
XP_518588
1445
161449
Y938
P
N
I
Y
I
L
D
Y
L
T
K
K
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001112898
1444
161598
Y937
P
N
I
Y
I
L
D
Y
L
T
K
K
K
Q
L
Dog
Lupus familis
XP_532205
1471
164964
Y964
P
N
I
Y
V
L
D
Y
L
T
K
K
R
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R422
1442
161640
Y940
P
N
I
Y
I
L
D
Y
L
T
K
Q
K
Q
L
Rat
Rattus norvegicus
P14046
1477
163755
P985
Q
N
M
V
L
F
A
P
N
I
Y
V
L
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20740
1473
166336
G964
S
V
V
G
D
I
M
G
T
A
I
Q
N
V
H
Frog
Xenopus laevis
NP_001128549
1474
163608
E941
G
D
D
H
P
K
T
E
E
I
S
L
K
V
P
Zebra Danio
Brachydanio rerio
XP_697512
1371
152989
L879
Q
Q
S
F
T
Q
T
L
F
L
E
F
L
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723299
1397
155090
M905
Y
G
C
G
E
Q
N
M
V
N
F
V
P
N
I
Honey Bee
Apis mellifera
XP_001122599
1236
139115
L744
K
A
T
A
N
S
I
L
A
G
N
S
V
N
R
Nematode Worm
Caenorhab. elegans
NP_493613
1501
166700
P1005
Q
N
M
L
N
L
V
P
N
I
L
V
V
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.8
86
N.A.
72.1
29.3
N.A.
N.A.
25.5
29.4
38.6
N.A.
31
30.6
31.7
N.A.
Protein Similarity:
100
99.5
96.6
91.7
N.A.
84.5
48.8
N.A.
N.A.
47
49.1
55.7
N.A.
51
49.8
52
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
6.6
N.A.
N.A.
0
6.6
0
N.A.
0
0
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
20
20
13.3
N.A.
20
0
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
9
0
9
9
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
0
42
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
9
9
0
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
9
0
0
9
0
9
9
0
0
0
% F
% Gly:
9
9
0
17
0
0
0
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
42
0
34
9
9
0
0
25
9
0
0
0
9
% I
% Lys:
9
0
0
0
0
9
0
0
0
0
42
34
42
17
0
% K
% Leu:
0
0
0
9
9
50
0
17
42
9
9
9
17
9
42
% L
% Met:
0
0
17
0
0
0
9
9
0
0
0
0
0
0
0
% M
% Asn:
0
59
0
0
17
0
9
0
17
9
9
0
9
17
0
% N
% Pro:
42
0
0
0
9
0
0
17
0
0
0
0
9
0
9
% P
% Gln:
25
9
0
0
0
17
0
0
0
0
0
17
0
42
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% R
% Ser:
9
0
9
0
0
9
0
0
0
0
9
9
0
0
0
% S
% Thr:
0
0
9
0
9
0
17
0
9
42
0
0
0
0
0
% T
% Val:
0
9
9
9
9
0
9
0
9
0
0
25
17
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
42
0
0
0
42
0
0
9
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _