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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD109
All Species:
19.09
Human Site:
Y967
Identified Species:
38.18
UniProt:
Q6YHK3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YHK3
NP_001153059.1
1445
161689
Y967
G
Y
Q
R
E
L
L
Y
Q
R
E
D
G
S
F
Chimpanzee
Pan troglodytes
XP_518588
1445
161449
Y967
G
Y
Q
R
E
L
L
Y
Q
R
E
D
G
S
F
Rhesus Macaque
Macaca mulatta
XP_001112898
1444
161598
Y966
G
Y
Q
R
E
L
L
Y
Q
R
E
D
G
S
F
Dog
Lupus familis
XP_532205
1471
164964
Y993
G
Y
Q
R
E
L
L
Y
Q
R
E
D
G
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R422
1442
161640
Y969
G
Y
Q
R
E
L
L
Y
Q
R
E
D
G
S
F
Rat
Rattus norvegicus
P14046
1477
163755
G1014
A
L
G
Y
L
R
A
G
Y
Q
R
E
L
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20740
1473
166336
Y993
V
L
F
A
P
N
I
Y
V
L
D
Y
L
D
K
Frog
Xenopus laevis
NP_001128549
1474
163608
A970
L
G
D
L
M
G
T
A
M
Q
N
L
D
R
L
Zebra Danio
Brachydanio rerio
XP_697512
1371
152989
R908
D
V
V
P
N
S
Q
R
A
S
V
S
A
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723299
1397
155090
K934
S
V
E
S
K
A
R
K
F
L
E
I
G
Y
Q
Honey Bee
Apis mellifera
XP_001122599
1236
139115
R773
R
A
T
F
L
D
L
R
N
T
K
S
T
S
I
Nematode Worm
Caenorhab. elegans
NP_493613
1501
166700
G1034
A
I
K
F
I
E
Q
G
I
Q
R
E
L
T
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.8
86
N.A.
72.1
29.3
N.A.
N.A.
25.5
29.4
38.6
N.A.
31
30.6
31.7
N.A.
Protein Similarity:
100
99.5
96.6
91.7
N.A.
84.5
48.8
N.A.
N.A.
47
49.1
55.7
N.A.
51
49.8
52
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
6.6
0
0
N.A.
13.3
13.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
20
6.6
0
N.A.
26.6
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
9
0
9
9
9
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
0
0
0
0
9
42
9
9
0
% D
% Glu:
0
0
9
0
42
9
0
0
0
0
50
17
0
0
0
% E
% Phe:
0
0
9
17
0
0
0
0
9
0
0
0
0
0
42
% F
% Gly:
42
9
9
0
0
9
0
17
0
0
0
0
50
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
9
0
9
0
0
9
0
0
9
% I
% Lys:
0
0
9
0
9
0
0
9
0
0
9
0
0
0
9
% K
% Leu:
9
17
0
9
17
42
50
0
0
17
0
9
25
0
9
% L
% Met:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
9
0
9
0
0
9
0
% N
% Pro:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
42
0
0
0
17
0
42
25
0
0
0
0
9
% Q
% Arg:
9
0
0
42
0
9
9
17
0
42
17
0
0
9
0
% R
% Ser:
9
0
0
9
0
9
0
0
0
9
0
17
0
50
0
% S
% Thr:
0
0
9
0
0
0
9
0
0
9
0
0
9
9
0
% T
% Val:
9
17
9
0
0
0
0
0
9
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
9
0
0
0
50
9
0
0
9
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _