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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 17.88
Human Site: S1174 Identified Species: 39.33
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 S1174 Y I Q A L L A S E P K K G R M
Chimpanzee Pan troglodytes XP_001141732 1953 219528 S1174 Y I Q A L L A S E P K K G R M
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 S1165 Y I Q A L L A S E P K K S R M
Rat Rattus norvegicus XP_233829 1937 217220 S1165 Y I Q A L L A S E P K K G R M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 A351 H A S D L L E A L F L S H R A
Chicken Gallus gallus A8C754 1930 216561 S1166 Y I Q A L L A S E P K K G K M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 L1041 L V G T E L K L G T H A T L Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 P961 L E T L H V T P Q M I L V C C
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 E1174 F I A L F L S E P D G A P K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 E1177 F I A L F L S E P E G S P K K
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 A715 A V L P G L K A F C I R C Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 93.3 100 N.A. 20 93.3 N.A. N.A. N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 93.3 100 N.A. 33.3 100 N.A. N.A. N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 19 46 0 0 46 19 0 0 0 19 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 10 10 10 % C
% Asp: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 10 0 0 10 0 10 19 46 10 0 0 0 0 0 % E
% Phe: 19 0 0 0 19 0 0 0 10 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 10 0 0 0 10 0 19 0 37 0 0 % G
% His: 10 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % H
% Ile: 0 64 0 0 0 0 0 0 0 0 19 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 19 0 0 0 46 46 0 28 19 % K
% Leu: 19 0 10 28 55 91 0 10 10 0 10 10 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 46 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 10 19 46 0 0 19 0 0 % P
% Gln: 0 0 46 0 0 0 0 0 10 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 46 0 % R
% Ser: 0 0 10 0 0 0 19 46 0 0 0 19 10 0 0 % S
% Thr: 0 0 10 10 0 0 10 0 0 10 0 0 10 0 0 % T
% Val: 0 19 0 0 0 10 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 46 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _