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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 11.52
Human Site: S1420 Identified Species: 25.33
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 S1420 L L Q A Y S D S K H G T N S D
Chimpanzee Pan troglodytes XP_001141732 1953 219528 S1420 L L Q A Y S D S K H G T N S D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 D1411 L L Q A Y I T D C R H R T N A
Rat Rattus norvegicus XP_233829 1937 217220 D1411 L L Q A Y I T D S K H R I N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 G590 E V L Q R Y Q G F L S S V C S
Chicken Gallus gallus A8C754 1930 216561 S1412 L L Q S Y L D S K Q L G N S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 T1280 K N T E A A N T K L N T N V L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 R1200 D H R V D V A R G I V S P F P
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 T1538 H M L S V A Q T G H I R E N Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 D1458 L L D T N C R D L A D N S K K
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 N954 V L H M L S E N F E E E I R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 33.3 33.3 N.A. 0 66.6 N.A. N.A. N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 40 40 N.A. 13.3 73.3 N.A. N.A. N.A. 40 N.A. N.A. 13.3
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: 40 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 37 10 19 10 0 0 10 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 10 0 0 10 0 0 0 0 10 0 % C
% Asp: 10 0 10 0 10 0 28 28 0 0 10 0 0 0 28 % D
% Glu: 10 0 0 10 0 0 10 0 0 10 10 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 19 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 10 19 0 19 10 0 0 0 % G
% His: 10 10 10 0 0 0 0 0 0 28 19 0 0 0 0 % H
% Ile: 0 0 0 0 0 19 0 0 0 10 10 0 19 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 37 10 0 0 0 10 19 % K
% Leu: 55 64 19 0 10 10 0 0 10 19 10 0 0 0 10 % L
% Met: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 10 10 0 0 10 10 37 28 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % P
% Gln: 0 0 46 10 0 0 19 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 0 10 10 0 10 0 28 0 10 0 % R
% Ser: 0 0 0 19 0 28 0 28 10 0 10 19 10 28 10 % S
% Thr: 0 0 10 10 0 0 19 19 0 0 0 28 10 0 0 % T
% Val: 10 10 0 10 10 10 0 0 0 0 10 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 46 10 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _