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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 15.45
Human Site: S1544 Identified Species: 34
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 S1544 R E T N V P I S F S Q L L E S
Chimpanzee Pan troglodytes XP_001141732 1953 219528 S1544 R E R N V P I S F S Q L L E S
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 S1536 Q A T A V P L S F S R L L K S
Rat Rattus norvegicus XP_233829 1937 217220 S1536 Q A T A V P L S F S Q L L K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 N713 V T A S Y M L N F L V H Q E A
Chicken Gallus gallus A8C754 1930 216561 A1536 S P T A M K I A K P P L S I V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 L1403 G I S Q G I V L H I V E D L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 T1323 P P N Q L V H T L H H L I D M
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 L1683 Q H W S K P N L Q E T M V K L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 S1607 L R C I S D Q S Y E V R L A T
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 Y1077 I L D M L L K Y E D S I Y L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 93.3 N.A. N.A. N.A. 60 66.6 N.A. 13.3 20 N.A. N.A. N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 93.3 N.A. N.A. N.A. 86.6 86.6 N.A. 40 33.3 N.A. N.A. N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 40 N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 28 0 0 0 10 0 0 0 0 0 10 19 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 0 0 0 10 0 0 10 10 10 % D
% Glu: 0 19 0 0 0 0 0 0 10 19 0 10 0 28 0 % E
% Phe: 0 0 0 0 0 0 0 0 46 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 10 0 10 10 10 10 0 0 0 % H
% Ile: 10 10 0 10 0 10 28 0 0 10 0 10 10 10 0 % I
% Lys: 0 0 0 0 10 10 10 0 10 0 0 0 0 28 0 % K
% Leu: 10 10 0 0 19 10 28 19 10 10 0 55 46 19 10 % L
% Met: 0 0 0 10 10 10 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 10 19 0 0 10 10 0 0 0 0 0 0 0 % N
% Pro: 10 19 0 0 0 46 0 0 0 10 10 0 0 0 0 % P
% Gln: 28 0 0 19 0 0 10 0 10 0 28 0 10 0 0 % Q
% Arg: 19 10 10 0 0 0 0 0 0 0 10 10 0 0 0 % R
% Ser: 10 0 10 19 10 0 0 46 0 37 10 0 10 0 37 % S
% Thr: 0 10 37 0 0 0 0 10 0 0 10 0 0 0 10 % T
% Val: 10 0 0 0 37 10 10 0 0 0 28 0 10 0 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 10 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _