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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 8.48
Human Site: S1933 Identified Species: 18.67
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 S1933 G E D T L V L S V W D S Y A E
Chimpanzee Pan troglodytes XP_001141732 1953 219528 S1933 G E D T L V L S V W D S Y A E
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 R1918 L E G K E G L R A E D C P R E
Rat Rattus norvegicus XP_233829 1937 217220 R1917 L E G K E V L R A E D C P R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 D1037 Y L R G E S E D L C P E L R L
Chicken Gallus gallus A8C754 1930 216561 L1911 N E Q I S L C L K I L N L L Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 G1727 T E L W D A R G R A D P R A R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 V1647 S S S S P L G V E P K M F V R
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 S2073 E D D M L L L S Q I V E I G K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 S2076 A E P A L L L S A K V T G G T
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 F1401 S P S D Y E N F I N V L T K H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 26.6 33.3 N.A. 0 6.6 N.A. N.A. N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 26.6 33.3 N.A. 6.6 26.6 N.A. N.A. N.A. 20 N.A. N.A. 20
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 26.6 N.A. N.A. 26.6 0 N.A.
P-Site Similarity: 46.6 N.A. N.A. 40 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 10 0 0 28 10 0 0 0 28 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 10 0 19 0 0 0 % C
% Asp: 0 10 28 10 10 0 0 10 0 0 46 0 0 0 0 % D
% Glu: 10 64 0 0 28 10 10 0 10 19 0 19 0 0 37 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % F
% Gly: 19 0 19 10 0 10 10 10 0 0 0 0 10 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 10 0 0 0 0 10 19 0 0 10 0 0 % I
% Lys: 0 0 0 19 0 0 0 0 10 10 10 0 0 10 10 % K
% Leu: 19 10 10 0 37 37 55 10 10 0 10 10 19 10 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 10 0 10 0 0 0 % N
% Pro: 0 10 10 0 10 0 0 0 0 10 10 10 19 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 0 10 0 0 0 10 19 10 0 0 0 10 28 19 % R
% Ser: 19 10 19 10 10 10 0 37 0 0 0 19 0 0 0 % S
% Thr: 10 0 0 19 0 0 0 0 0 0 0 10 10 0 10 % T
% Val: 0 0 0 0 0 28 0 10 19 0 28 0 0 10 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 19 0 0 0 0 0 % W
% Tyr: 10 0 0 0 10 0 0 0 0 0 0 0 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _