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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THADA
All Species:
15.45
Human Site:
S375
Identified Species:
34
UniProt:
Q6YHU6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YHU6
NP_001077422.1
1953
219607
S375
I
Q
V
L
E
S
S
S
P
S
L
T
D
S
L
Chimpanzee
Pan troglodytes
XP_001141732
1953
219528
S375
I
Q
V
L
E
S
S
S
P
S
L
T
D
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
A8C756
1938
217270
S375
I
Q
I
L
E
S
G
S
S
G
L
K
G
H
L
Rat
Rattus norvegicus
XP_233829
1937
217220
S375
I
Q
I
L
E
S
S
S
P
S
L
K
D
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513110
1056
113729
Chicken
Gallus gallus
A8C754
1930
216561
S377
L
A
A
L
I
P
D
S
P
N
L
K
V
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608361
1746
197334
F273
L
A
R
F
S
G
T
F
K
A
Y
V
E
D
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797130
1666
185673
R193
K
S
V
P
D
L
S
R
L
Y
L
C
H
G
F
Poplar Tree
Populus trichocarpa
XP_002305983
2134
240562
T359
I
C
L
Q
Q
M
K
T
S
M
L
S
N
L
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191076
2149
242725
C381
V
L
T
V
M
Q
I
C
M
Q
Q
I
K
T
S
Baker's Yeast
Sacchar. cerevisiae
Q03496
1420
163559
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
N.A.
N.A.
78.4
79.2
N.A.
30.9
58.1
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
23.4
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
87.4
87.5
N.A.
39.8
73
N.A.
N.A.
N.A.
40.1
N.A.
N.A.
40.5
P-Site Identity:
100
100
N.A.
N.A.
N.A.
53.3
80
N.A.
0
33.3
N.A.
N.A.
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
60
86.6
N.A.
0
46.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
20.4
N.A.
N.A.
20.8
21.2
N.A.
Protein Similarity:
39
N.A.
N.A.
39.9
38.7
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
28
10
0
% D
% Glu:
0
0
0
0
37
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
10
10
0
0
10
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
19
0
% H
% Ile:
46
0
19
0
10
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
10
0
0
28
10
10
0
% K
% Leu:
19
10
10
46
0
10
0
0
10
0
64
0
0
10
46
% L
% Met:
0
0
0
0
10
10
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
10
0
0
37
0
0
0
0
0
0
% P
% Gln:
0
37
0
10
10
10
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
10
37
37
46
19
28
0
10
0
19
10
% S
% Thr:
0
0
10
0
0
0
10
10
0
0
0
19
0
10
10
% T
% Val:
10
0
28
10
0
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _