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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 18.18
Human Site: S839 Identified Species: 40
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 S839 A A L E L S T S T K P Y D C V
Chimpanzee Pan troglodytes XP_001141732 1953 219528 S839 A A L E L S T S T K P Y D C V
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 S831 A A L E L S T S T K P Y D C V
Rat Rattus norvegicus XP_233829 1937 217220 S831 A A L E L S T S T K P Y D C V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 Q29 G R F V S V L Q F L Q K V L L
Chicken Gallus gallus A8C754 1930 216561 S831 A A M D L S T S T K P Y D C V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 L719 N K V L A A Q L L E R F Q S H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 P639 L N L N N P S P S F R Q Q L I
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 I834 T L L L V G S I I D S W D R L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 R842 R L R E N S F R I L L H F P T
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 R393 Y S L A R D A R K L K K A E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 100 100 N.A. 0 86.6 N.A. N.A. N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 100 N.A. 6.6 100 N.A. N.A. N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 40 N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 46 0 10 10 10 10 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 % C
% Asp: 0 0 0 10 0 10 0 0 0 10 0 0 55 0 0 % D
% Glu: 0 0 0 46 0 0 0 0 0 10 0 0 0 10 0 % E
% Phe: 0 0 10 0 0 0 10 0 10 10 0 10 10 0 0 % F
% Gly: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 10 19 0 0 0 0 0 10 % I
% Lys: 0 10 0 0 0 0 0 0 10 46 10 19 0 0 10 % K
% Leu: 10 19 64 19 46 0 10 10 10 28 10 0 0 19 19 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 19 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 10 0 0 46 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 10 10 0 0 10 10 19 0 0 % Q
% Arg: 10 10 10 0 10 0 0 19 0 0 19 0 0 10 0 % R
% Ser: 0 10 0 0 10 55 19 46 10 0 10 0 0 10 0 % S
% Thr: 10 0 0 0 0 0 46 0 46 0 0 0 0 0 10 % T
% Val: 0 0 10 10 10 10 0 0 0 0 0 0 10 0 46 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 46 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _